CAS No.:1421-14-3
Name: Propanidide
Details Introduction
TOXICITY DATA with REFERENCE：
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| cat | LD50 | intravenous | 80mg/kg (80mg/kg) | Acta Anaesthesiologica Scandinavica, Supplementum. Vol. 17, Pg. 21, 1965. | |
| dog | LD50 | intravenous | 80mg/kg (80mg/kg) | Acta Anaesthesiologica Scandinavica, Supplementum. Vol. 17, Pg. 21, 1965. | |
| human | TDLo | intravenous | 5mg/kg (5mg/kg) | BEHAVIORAL: GENERAL ANESTHETIC | British Journal of Anesthesia. Vol. 45, Pg. 1097, 1973. |
| mouse | LD50 | intravenous | 113mg/kg (113mg/kg) | Oyo Yakuri. Pharmacometrics. Vol. 19, Pg. 845, 1980. | |
| rabbit | LD50 | intravenous | 75mg/kg (75mg/kg) | Acta Anaesthesiologica Scandinavica, Supplementum. Vol. 17, Pg. 21, 1965. | |
| rat | LD50 | intravenous | 81mg/kg (81mg/kg) | Acta Anaesthesiologica Scandinavica, Supplementum. Vol. 17, Pg. 21, 1965. | |
| rat | LD50 | oral | > 10gm/kg (10000mg/kg) | Toxicology and Applied Pharmacology. Vol. 18, Pg. 185, 1971. |
Consensus Reports：
SAFETY PROFILE：
Poison by intravenous route. Moderately toxic by ingestion. An experimental teratogen. Experimental reproductive effects. Human systemic effects by intravenous route: general anesthesia. When Propanidide (CAS NO.1421-14-3) is heated to decomposition, it emits toxic fumes of NOx.
Standards and Recommendations：
Analytical Methods：
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