CAS No.:22760-18-5

TOXICITY DATA with REFERENCE：

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD	oral	> 800mg/kg (800mg/kg)	SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)	Drug and Chemical Toxicology. Vol. 3, Pg. 361, 1980.
mouse	LD50	intraperitoneal	339mg/kg (339mg/kg)	BEHAVIORAL: GENERAL ANESTHETIC BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)	Arzneimittel-Forschung. Drug Research. Vol. 34, Pg. 879, 1984.
mouse	LD50	oral	930mg/kg (930mg/kg)	SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)	Drug and Chemical Toxicology. Vol. 3, Pg. 361, 1980.
rabbit	LD50	oral	260mg/kg (260mg/kg)	SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: ANTIPSYCHOTIC	Drug and Chemical Toxicology. Vol. 3, Pg. 361, 1980.
rat	LD50	intraperitoneal	375mg/kg (375mg/kg)	SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: ANTIPSYCHOTIC	Drug and Chemical Toxicology. Vol. 3, Pg. 361, 1980.
rat	LD50	oral	759mg/kg (759mg/kg)	SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)	Drug and Chemical Toxicology. Vol. 3, Pg. 361, 1980.

Consensus Reports：

 

SAFETY PROFILE：

Poison by ingestion and intraperitoneal routes. When heated to decomposition it emits toxic fumes of NO_x.

Standards and Recommendations：

 

Analytical Methods：