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Current position:Home > Products > Pyrazinamide

CAS No.:98-96-4

Name: Pyrazinamide

Details Introduction

TOXICITY DATA with REFERENCE:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 1680mg/kg (1680mg/kg)   Chemotherapia. Vol. 5, Pg. 39, 1962.
mouse LD50 subcutaneous 2973mg/kg (2973mg/kg)   Drugs in Japan Vol. -, Pg. 1038, 1995.
mouse LDLo oral 3gm/kg (3000mg/kg) BEHAVIORAL: EXCITEMENT

BEHAVIORAL: ATAXIA
American Review of Tuberculosis. Vol. 70, Pg. 423, 1954.
rat LDLo oral 3gm/kg (3000mg/kg) BEHAVIORAL: EXCITEMENT

BEHAVIORAL: ATAXIA
American Review of Tuberculosis. Vol. 70, Pg. 423, 1954.
women TDLo oral 10mg/kg (10mg/kg) VASCULAR: BP ELEVATION NOT CHARACTERIZED IN AUTONOMIC SECTION JAMA, Journal of the American Medical Association. Vol. 127, Pg. 1356, 1997.


Consensus Reports:

 


SAFETY PROFILE:

Hazard Codes: FlammableF, Corrosive
Risk Statements: 11-34 
R11:Highly flammable. 
R34:Causes burns.
Safety Statements: 22-24/25-45-36/37/39-26-16 
S22:Do not breathe dust. 
S24/25:Avoid contact with skin and eyes. 
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) 
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection. 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S16:Keep away from sources of ignition.
WGK Germany: 3
RTECS of Pyrazinamide (CAS NO.98-96-4): UQ2275000


Standards and Recommendations:

 


Analytical Methods:

 


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