CAS No.:98-96-4
Name: Pyrazinamide
Details Introduction
TOXICITY DATA with REFERENCE:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intraperitoneal | 1680mg/kg (1680mg/kg) | Chemotherapia. Vol. 5, Pg. 39, 1962. | |
mouse | LD50 | subcutaneous | 2973mg/kg (2973mg/kg) | Drugs in Japan Vol. -, Pg. 1038, 1995. | |
mouse | LDLo | oral | 3gm/kg (3000mg/kg) | BEHAVIORAL: EXCITEMENT BEHAVIORAL: ATAXIA |
American Review of Tuberculosis. Vol. 70, Pg. 423, 1954. |
rat | LDLo | oral | 3gm/kg (3000mg/kg) | BEHAVIORAL: EXCITEMENT BEHAVIORAL: ATAXIA |
American Review of Tuberculosis. Vol. 70, Pg. 423, 1954. |
women | TDLo | oral | 10mg/kg (10mg/kg) | VASCULAR: BP ELEVATION NOT CHARACTERIZED IN AUTONOMIC SECTION | JAMA, Journal of the American Medical Association. Vol. 127, Pg. 1356, 1997. |
Consensus Reports:
SAFETY PROFILE:
Hazard Codes: F,
C
Risk Statements: 11-34
R11:Highly flammable.
R34:Causes burns.
Safety Statements: 22-24/25-45-36/37/39-26-16
S22:Do not breathe dust.
S24/25:Avoid contact with skin and eyes.
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S16:Keep away from sources of ignition.
WGK Germany: 3
RTECS of Pyrazinamide (CAS NO.98-96-4): UQ2275000
Standards and Recommendations:
Analytical Methods:
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