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CAS No.:54-47-7

Name: Pyridoxal phosphate

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Details Introduction

TOXICITY DATA with REFERENCE:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mammal (species unspecified) LD50 oral > 3gm/kg (3000mg/kg)   British Patent Document. Vol. #1172800,
mammal (species unspecified) LD50 subcutaneous 550mg/kg (550mg/kg)   British Patent Document. Vol. #1172800,
mouse LD50 intramuscular 1150mg/kg (1150mg/kg) BEHAVIORAL: ANTIPSYCHOTIC Pharmaceutical Chemistry Journal Vol. 15, Pg. 303, 1981.
mouse LD50 intravenous 530mg/kg (530mg/kg)   Drugs in Japan Vol. 6, Pg. 643, 1982.
mouse LD50 oral 4640mg/kg (4640mg/kg)   Drugs in Japan Vol. 6, Pg. 643, 1982.
mouse LD50 subcutaneous 870mg/kg (870mg/kg)   Drugs in Japan Vol. 6, Pg. 643, 1982.
rat LD50 oral 5900mg/kg (5900mg/kg)   Drugs in Japan Vol. 6, Pg. 643, 1982.
rat LD50 subcutaneous 850mg/kg (850mg/kg)   Drugs in Japan Vol. 6, Pg. 643, 1982.


Consensus Reports:

Reported in EPA TSCA Inventory.


SAFETY PROFILE:

Moderately toxic subcutaneous, intravenous, and intramuscular routes. Mildly toxic by ingestion. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx and POx.
Safety Statements: 22-24/25 
S22: Do not breathe dust. 
S24/25: Avoid contact with skin and eyes.
WGK Germany: 3
F: 8-10-23


Standards and Recommendations:

 


Analytical Methods:

 


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