CAS No.:545-93-7

TOXICITY DATA with REFERENCE：

1.		ipr-rbt LDLo:60 mg/kg		JPETAB    Journal of Pharmacology and Experimental Therapeutics. 44 (1932),325.
2.		scu-rat LD50:90 mg/kg		AEPPAE    Naunyn-Schmiedeberg’s Archiv fuer Experimentelle Pathologie und Pharmakologie. 152 (1930),341.
3.		scu-mus LDLo:100 mg/kg		HBAMAK    “Abdernalden’s Handbuch der Biologischen Arbeitsmethoden.“ 4 (1935),1289.
4.		orl-rbt LDLo:225 mg/kg		JPETAB    Journal of Pharmacology and Experimental Therapeutics. 44 (1932),325.
5.		ipr-rbt LDLo:120 mg/kg		JPETAB    Journal of Pharmacology and Experimental Therapeutics. 44 (1932),325.
6.		scu-gpg LDLo:80 mg/kg		HBAMAK    “Abdernalden’s Handbuch der Biologischen Arbeitsmethoden.“ 4 (1935),1289.
7.		scu-frg LDLo:300 mg/kg		HBAMAK    “Abdernalden’s Handbuch der Biologischen Arbeitsmethoden.“ 4 (1935),1289.
8.		orl-mam LDLo:300 mg/kg		JPETAB    Journal of Pharmacology and Experimental Therapeutics. 42 (1931),253.

Consensus Reports：

 

SAFETY PROFILE：

Poison by ingestion, intraperitoneal, and subcutaneous routes. Used as a sedative and hypnotic agent. When heated to decomposition it emits very toxic fumes of NO_x and Br⁻. A controlled drug under 21 CFR 1308.11, which may be habit forming. See also BARBITURATES.
RIDADR 3249
HazardClass 6.1(b)
PackingGroup III

Standards and Recommendations：

 

Analytical Methods：