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CAS No.:66-32-0

Name: STRYCHNINE MONONITRATE

Details Introduction

TOXICITY DATA with REFERENCE：

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
cat	LDLo	oral	2mg/kg (2mg/kg)		Yakkyoku. Pharmacy. Vol. 28, Pg. 329, 1977.
dog	LDLo	oral	1gm/kg (1000mg/kg)		Yakkyoku. Pharmacy. Vol. 28, Pg. 329, 1977.
guinea pig	LDLo	intraarterial	1200ug/kg (1.2mg/kg)		Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 131, Pg. 171, 1928.
guinea pig	LDLo	intravenous	1mg/kg (1mg/kg)		Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 131, Pg. 171, 1928.
human	LDLo	oral	500ug/kg (0.5mg/kg)		Yakkyoku. Pharmacy. Vol. 28, Pg. 329, 1977.
mouse	LD50	oral	930ug/kg (0.93mg/kg)		Journal of Toxicology, Clinical Toxicology. Vol. 22, Pg. 425, 1984.
mouse	LD50	unreported	900ug/kg (0.9mg/kg)		Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 207, Pg. 688, 1949.
mouse	LDLo	intravenous	600ug/kg (0.6mg/kg)	behavioral: convulsions or effect on seizure threshold	Arzneimittel-Forschung. Drug Research. Vol. 20, Pg. 1778, 1970.
mouse	LDLo	subcutaneous	2mg/kg (2mg/kg)	behavioral: convulsions or effect on seizure threshold	Arzneimittel-Forschung. Drug Research. Vol. 17, Pg. 458, 1967.
pig	LDLo	oral	20ug/kg (0.02mg/kg)		Yakkyoku. Pharmacy. Vol. 28, Pg. 329, 1977.
rabbit	LD50	intravenous	250ug/kg (0.25mg/kg)	behavioral: convulsions or effect on seizure threshold	Pharmacology and Toxicology. English translation of FATOAO. Vol. 21, Pg. 1, 1958.
rat	LD50	oral	16200ug/kg (16.2mg/kg)		Drugs in Japan Vol. 6, Pg. 377, 1982.
rat	LDLo	intravenous	600ug/kg (0.6mg/kg)	behavioral: convulsions or effect on seizure threshold	Arzneimittel-Forschung. Drug Research. Vol. 20, Pg. 1778, 1970.
rat	LDLo	subcutaneous	3mg/kg (3mg/kg)	behavioral: convulsions or effect on seizure threshold behavioral: tetany	Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 187, Pg. 607, 1937

Consensus Reports：

SAFETY PROFILE：

Hazard Codes: T+
Risk Statements : 26/27/28
26/27/28: Strychnine mononitrate (66-32-0) is very Toxic by inhalation, in contact with skin and if swallowed
Safety Statements : 22-36/37/39-45
22: Do not breathe dust
45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
36/37/39:When Strychnine mononitrate (66-32-0) used,wear suitable protective clothing, gloves and eye/face protection
RIDADR : UN 1692 6.1/PG 1
WGK Germany: 3
RTECS : WL2450000
HazardClass: 6.1(a).

Standards and Recommendations：

Analytical Methods：

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CAS No.:66-32-0

Name: STRYCHNINE MONONITRATE