CAS No.:642-78-4

TOXICITY DATA with REFERENCE：

1.		orl-rat LD50:5 g/kg		NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),232.
2.		ipr-rat LD50:1350 mg/kg		ARZNAD    Arzneimittel-Forschung. Drug Research. 15 (1965),322.
3.		scu-rat LD50:4200 mg/kg		NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),232.
4.		ivn-rat LD50:1660 mg/kg		NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),232.
5.		orl-mus LD50:5 g/kg		NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),232.
6.		ipr-mus LD50:1170 mg/kg		NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),232.
7.		scu-mus LD50:1500 mg/kg		NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),232.
8.		ivn-mus LD50:916 mg/kg		FATOAO    Farmakologiya i Toksikologiya (Moscow). 31 (1968),232.
9.		ims-mus LD50:1220 mg/kg		NIIRDN

Consensus Reports：

 

SAFETY PROFILE：

Safety Information of Cloxacillin sodium (CAS NO.642-78-4):
Hazard Codes: Xn 
Risk Statements: 36/37/38-42/43
R36/37/38:Irritating to eyes, respiratory system and skin
R42/43:May cause sensitization by inhalation and skin contact
Safety Statements: 26-36-22
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36:Wear suitable protective clothing
S22:Do not breathe dust
WGK Germany: 2
RTECS: XH8920000
Moderately toxic by intraperitoneal, subcutaneous, intramuscular, and intravenous routes. Mildly toxic by ingestion. When heated to decomposition it emits very toxic fumes of Cl⁻, NO_x, SO_x, Na₂O.

Standards and Recommendations：

 

Analytical Methods：