CAS No.:110-61-2
Name: Succinonitrile
Details Introduction
TOXICITY DATA with REFERENCE:
dog | LDLo | subcutaneous | 150mg/kg (150mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD GASTROINTESTINAL: NAUSEA OR VOMITING |
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 3, Pg. 77, 1897. |
frog | LDLo | subcutaneous | 1gm/kg (1000mg/kg) | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 3, Pg. 77, 1897. | |
mouse | LD50 | intraperitoneal | 63110ug/kg (63.11mg/kg) | KIDNEY, URETER, AND BLADDER: OTHER CHANGES IN URINE COMPOSITION | Biochemical Pharmacology. Vol. 27, Pg. 1135, 1978. |
mouse | LD50 | oral | 129mg/kg (129mg/kg) | Archives of Toxicology. Vol. 57, Pg. 88, 1985. | |
pigeon | LDLo | subcutaneous | 2200mg/kg (2200mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD GASTROINTESTINAL: NAUSEA OR VOMITING |
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 3, Pg. 77, 1897. |
rabbit | LDLo | subcutaneous | 36mg/kg (36mg/kg) | PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 3, Pg. 77, 1897. |
rat | LCLo | inhalation | 730mg/m3/4H (730mg/m3) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA |
National Technical Information Service. Vol. OTS0570875, |
rat | LD50 | oral | 450mg/kg (450mg/kg) | "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2C, Pg. 4879, 1982. |
Consensus Reports:
Cyanide and its compounds are on the Community Right-To-Know List. Reported in EPA TSCA Inventory.
SAFETY PROFILE:
Hazard Codes: Xn
Risk Statements: 22-36/37/38-36/38-20/21/22
R22:Harmful if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin.
R36/38:Irritating to eyes and skin.
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.
Safety Statements: 26-36/37-45-36/37/39-22
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37:Wear suitable protective clothing and gloves.
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
S22:Do not breathe dust.
RIDADR: 3276
WGK Germany: 3
RTECS: WN3850000
HazardClass: 6.1
PackingGroup: III
HS Code: 29051900
HS Code: 29269095
Poison by ingestion, intraperitoneal, and subcutaneous routes. An experimental teratogen. Combustible when exposed to heat or flame. Decomposes exothermically above 195°C. Can react with oxidizing materials. To fight fire, use alcohol foam, CO2, dry chemical. When heated to decomposition, or on contact with acid or acid fumes, it emits highly toxic fumes of NOx and CN−. See also NITRILES.
Standards and Recommendations:
ACGIH TLV: CL 5 mg(CN)/m3 (skin)
NIOSH REL: (Nitriles) TWA 20 mg/m3
Analytical Methods:
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