CAS No.:467-36-7
Name: Thialbarbital
Details Introduction
TOXICITY DATA with REFERENCE：
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intraperitoneal | 384mg/kg (384mg/kg) | British Journal of Pharmacology and Chemotherapy. Vol. 1, Pg. 215, 1946. | |
| mouse | LD50 | intravenous | 390mg/kg (390mg/kg) | British Journal of Pharmacology and Chemotherapy. Vol. 1, Pg. 215, 1946. | |
| mouse | LD50 | oral | 370mg/kg (370mg/kg) | British Journal of Pharmacology and Chemotherapy. Vol. 1, Pg. 215, 1946. | |
| mouse | LD50 | subcutaneous | 240mg/kg (240mg/kg) | Farmaco. Scienza e Tecnica. Vol. 3, Pg. 269, 1948. | |
| rat | LD50 | intravenous | 175mg/kg (175mg/kg) | BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 106, Pg. 437, 1956. |
Consensus Reports：
SAFETY PROFILE：
Poison by ingestion, intraperitoneal and intravenous routes. When heated to decomposition Thialbarbital (CAS NO.467-36-7) emits very toxic fumes of NOx and SOx. See also BARBITURATES.
Standards and Recommendations：
Analytical Methods：
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