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Current position:Home > Products > Timiperone

CAS No.:57648-21-2

Name: Timiperone

Details Introduction

TOXICITY DATA with REFERENCE:

dog LD50 intravenous 20mg/kg (20mg/kg)   Drugs in Japan Vol. -, Pg. 647, 1990.
dog LD50 oral 85mg/kg (85mg/kg)   Drugs in Japan Vol. -, Pg. 647, 1990.
mouse LD50 oral 500mg/kg (500mg/kg)   Journal of Medicinal Chemistry. Vol. 21, Pg. 1116, 1978.
rabbit LD50 oral 237mg/kg (237mg/kg)   Drugs in Japan Vol. -, Pg. 647, 1990.
rat LD50 intravenous > 12100ug/kg (12.1mg/kg)   Drugs in Japan Vol. -, Pg. 647, 1990.
rat LD50 oral 232mg/kg (232mg/kg)   Japanese Journal of Pharmacology. Vol. 27(Suppl), Pg. 124P, 1977.
rat LD50 subcutaneous > 2600mg/kg (2600mg/kg)   Drugs in Japan Vol. -, Pg. 647, 1990.


Consensus Reports:

 


SAFETY PROFILE:

Moderately toxic by ingestion. An experimental teratogen. Experimental reproductive effects. Used as a tranquilizer. When heated to decomposition it emits toxic fumes of F, SOx, and NOx.


Standards and Recommendations:

 


Analytical Methods:

 


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