CAS No.:57648-21-2
Name: Timiperone
Details Introduction
TOXICITY DATA with REFERENCE:
dog | LD50 | intravenous | 20mg/kg (20mg/kg) | Drugs in Japan Vol. -, Pg. 647, 1990. | |
dog | LD50 | oral | 85mg/kg (85mg/kg) | Drugs in Japan Vol. -, Pg. 647, 1990. | |
mouse | LD50 | oral | 500mg/kg (500mg/kg) | Journal of Medicinal Chemistry. Vol. 21, Pg. 1116, 1978. | |
rabbit | LD50 | oral | 237mg/kg (237mg/kg) | Drugs in Japan Vol. -, Pg. 647, 1990. | |
rat | LD50 | intravenous | > 12100ug/kg (12.1mg/kg) | Drugs in Japan Vol. -, Pg. 647, 1990. | |
rat | LD50 | oral | 232mg/kg (232mg/kg) | Japanese Journal of Pharmacology. Vol. 27(Suppl), Pg. 124P, 1977. | |
rat | LD50 | subcutaneous | > 2600mg/kg (2600mg/kg) | Drugs in Japan Vol. -, Pg. 647, 1990. |
Consensus Reports:
SAFETY PROFILE:
Moderately toxic by ingestion. An experimental teratogen. Experimental reproductive effects. Used as a tranquilizer. When heated to decomposition it emits toxic fumes of F−, SOx, and NOx.
Standards and Recommendations:
Analytical Methods:
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