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CAS No.:57524-15-9

Name: Tolonidine nitrate

Details Introduction

TOXICITY DATA with REFERENCE:

1.    

orl-rat LD50:420 mg/kg

    ARZNAD    Arzneimittel-Forschung. Drug Research. 25 (1975),1926.
2.    

ivn-rat LD50:42 mg/kg

    ARZNAD    Arzneimittel-Forschung. Drug Research. 25 (1975),1926.
3.    

orl-mus LD50:160 mg/kg

    ARZNAD    Arzneimittel-Forschung. Drug Research. 25 (1975),1926.
4.    

ivn-mus LD50:18,500 µg/kg

    ARZNAD    Arzneimittel-Forschung. Drug Research. 25 (1975),1926.

Consensus Reports:

 


SAFETY PROFILE:

Poison by ingestion and intravenous routes. Used as an antihypertensive agent. When heated to decomposition it emits toxic fumes of Cl and NOx. See also NITRATES.


Standards and Recommendations:

 


Analytical Methods:

 


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