CAS No.:52-53-9
Name: Verapamil
Details Introduction
TOXICITY DATA with REFERENCE:
| 1. |
ivn-man TDLo:1429 µg/kg/5M-C:CVS,PUL,SKN |
NEJMAG New England Journal of Medicine. 306 (1982),238. | ||
| 2. |
orl-wmn TDLo:64 mg/kg |
BMJOAE British Medical Journal. 2 (1978),1127. | ||
| 3. |
orl-man TDLo:48 mg/kg/2W-I |
NEJMAG New England Journal of Medicine. 306 (1982),612. | ||
| 4. |
orl-man LDLo:83 mg/kg |
AJEMEN American Journal of Emergency Medicine. 7 (1989),624. | ||
| 5. |
ivn-man TDLo:1429 µg/kg/5M-C |
NEJMAG New England Journal of Medicine. 306 (1982),238. | ||
| 6. |
ivn-man TDLo:71 µg/kg |
AHJOA2 American Heart Journal. 111 (1986),622. | ||
| 7. |
ivn-cld TDLo:250 µg/kg/5M-C |
AHJOA2 American Heart Journal. 106 (1983),145. | ||
| 8. |
orl-rat LD50:163 mg/kg |
EJMCA5 European Journal of Medicinal Chemistry. Chimie Therapeutique. 25 (1990),351. | ||
| 9. |
ipr-rat LD50:67 mg/kg |
ARZNAD Arzneimittel-Forschung. Drug Research. 31 (1981),1401. | ||
| 10. |
ivn-rat LD50:7250 µg/kg |
PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. 22 (1988),123. |
Consensus Reports:ISOPTIN's consensus:
Cyanide and its compounds are on the Community Right-To-Know List.
SAFETY PROFILE:
ISOPTIN's safety:
A poison by ingestion, subcutaneous, intraperitoneal, and intravenous routes. When heated to decomposition it emits toxic fumes of NOx and CN−. See also NITRILES.
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