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Current position:Home > Products > ZEARALENONE

CAS No.:17924-92-4

Name: ZEARALENONE

Details Introduction

TOXICITY DATA with REFERENCE:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
domestic animals - goat/sheep LD50 oral > 5mg/kg (5mg/kg)   Veterinary and Human Toxicology. Vol. 25, Pg. 335, 1983.
mouse LD oral > 2gm/kg (2000mg/kg)   National Toxicology Program Technical Report Series. Vol. NTP-TR-235, Pg. 1982,
mouse LD50 intraperitoneal 5mg/kg (5mg/kg)   Veterinary and Human Toxicology. Vol. 25, Pg. 335, 1983.
rat LD50 oral > 16gm/kg (16000mg/kg)   Toxicology and Applied Pharmacology. Vol. 37, Pg. 144, 1976.


Consensus Reports:

IARC Cancer Review: Group 3 IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 ,1987,p. 56.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Human Inadequate Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 31 ,1983,p. 279.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Limited Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 31 ,1983,p. 279.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . NTP Carcinogenesis Bioassay (feed); Clear Evidence: mouse NTPTR*    National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No. 206- NTP-TR-235 ,1982. ; (feed); No Evidence: rat NTPTR*    National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No. 206- NTP-TR-235 ,1982. . Reported in EPA TSCA Inventory. EPA Genetic Toxicology Program.


SAFETY PROFILE:

Experimental reproductive effects. Questionable carcinogen with experimental neoplastigenic, tumorigenic, and teratogenic data. Mutation data reported. A severe skin irritant. When heated to decomposition it emits acrid smoke and irritating fumes.
Flash point data for Zearalenone are not available. Zearalenone is probably combustible.
Safety Information of Zearalenone (17924-92-4):
Hazard Codes: C,Xn,F
Risk Statements: 34-62-63-36-20/21/22-11
11:  Highly Flammable 
20:  Harmful by inhalation 
21:  Harmful in contact with skin 
22:  Harmful if swallowed
34:  Causes burns  
36:  Irritating to the eyes 
62:  Possible risk of impaired fertility 
63:  Possible risk of harm to the unborn child 
Safety Statements: 26-36/37/39-45-36-16-36/37
16:  Keep away from sources of ignition - No smoking
26:  In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36:  Wear suitable protective clothing  
37:  Wear suitable gloves 
39:  Wear eye/face protection
45:  In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)


Standards and Recommendations:

 


Analytical Methods:

 


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