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CAS No.:43200-80-2

Name: Zopiclone

Details Introduction

TOXICITY DATA with REFERENCE:

1.    

orl-rat LD50:827 mg/kg

    OYYAA2    Oyo Yakuri. Pharmacometrics. 26 (1983),935.
2.    

ipr-rat LD50:771 mg/kg

    OYYAA2    Oyo Yakuri. Pharmacometrics. 26 (1983),935.
3.    

scu-rat LD50:540 mg/kg

    OYYAA2    Oyo Yakuri. Pharmacometrics. 26 (1983),935.
4.    

ivn-rat LD50:280 mg/kg

    OYYAA2    Oyo Yakuri. Pharmacometrics. 26 (1983),935.
5.    

ims-rat LD50:295 mg/kg

    OYYAA2    Oyo Yakuri. Pharmacometrics. 26 (1983),935.
6.    

orl-mus LD50:2174 mg/kg

    OYYAA2    Oyo Yakuri. Pharmacometrics. 26 (1983),935.
7.    

ipr-mus LD50:1325 mg/kg

    OYYAA2    Oyo Yakuri. Pharmacometrics. 26 (1983),935.
8.    

scu-mus LD50:888 mg/kg

    OYYAA2    Oyo Yakuri. Pharmacometrics. 26 (1983),935.
9.    

ivn-mus LD50:321 mg/kg

    OYYAA2    Oyo Yakuri. Pharmacometrics. 26 (1983),935.
10.    

ims-mus LD50:541 mg/kg

    OYYAA2    Oyo Yakuri. Pharmacometrics. 26 (1983),935.

Consensus Reports:

 


SAFETY PROFILE:

Hazard Codes: HarmfulXn,IrritantXi
Risk Statements: 20/21/22-36/37/38-62
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed. 
R36/37/38:Irritating to eyes, respiratory system and skin. 
R62:Risk of impaired fertility.
Safety Statements: 26-36
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36:Wear suitable protective clothing.
WGK Germany: 3
RTECS: TL1425000


Standards and Recommendations:

 


Analytical Methods:

 


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