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CAS No.:125-58-6

Name: l-Methadone

Details Introduction

TOXICITY DATA with REFERENCE:

1.    

dni-rat:tes 50 µmol/L

    BCPCA6    Biochemical Pharmacology. 27 (1978),123.
2.    

oms-rat:tes 50 µmol/L

    BCPCA6    Biochemical Pharmacology. 27 (1978),123.
3.    

orl-mus LD50:97 mg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 198 (1976),340.
4.    

ipr-mus LD50:32 mg/kg

    BJPCAL    British Journal of Pharmacology and Chemotherapy. 9 (1954),280.
5.    

scu-mus LD50:26,500 µg/kg

    MEXPAG    Medicina Experimentalis. 2 (1960),323.

Consensus Reports:

 


SAFETY PROFILE:

Poison by ingestion, subcutaneous, and intraperitoneal routes. Experimental reproductive effects. Mutation data reported. Caution: Abuse leads to habituation or addiction. When heated to decomposition it emits toxic fumes of NOx. See also METHADONE HYDROCHLORIDE.


Standards and Recommendations:

 


Analytical Methods:

 


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