CAS No.:638-03-9
Name: m-Toluidine hydrochloride
Details Introduction
TOXICITY DATA with REFERENCE:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
frog | LDLo | subcutaneous | 574mg/kg (574mg/kg) | AUTONOMIC NERVOUS SYSTEM: OTHER (DIRECT) PARASYMPATHOMIMETIC | Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 130, Pg. 250, 1928. |
mouse | LD50 | intraperitoneal | 650mg/kg (650mg/kg) | Progress Report for Contract No. NIH-NCI-E-68-1311, Submitted to the National Cancer Institut by Bio-Research Consultants, Inc. Vol. NCI-E-68-1311, Pg. 1973, | |
rat | LD50 | intraperitoneal | 660mg/kg (660mg/kg) | Journal of Environmental Pathology and Toxicology. Vol. 2(2), Pg. 325, 1978. |
Consensus Reports:
SAFETY PROFILE:
Moderately toxic by subcutaneous and intraperitoneal routes. Questionable carcinogen with experimental tumorigenic data. When heated to decomposition it emits very toxic fumes of NOx and HCl. See also m-TOLUIDINE.
RTECS XU7175000
Standards and Recommendations:
Analytical Methods:
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