CAS No.:24342-56-1
Name: ortho-Methylcyclizine dihydrochloride
Details Introduction
TOXICITY DATA with REFERENCE：
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intramuscular | 90mg/kg (90mg/kg) | BEHAVIORAL: TREMOR BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: EXCITEMENT |
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 116, Pg. 17, 1958. |
| mouse | LD50 | intraperitoneal | 70mg/kg (70mg/kg) | BEHAVIORAL: TREMOR BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: EXCITEMENT |
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 116, Pg. 17, 1958. |
| mouse | LD50 | oral | 142mg/kg (142mg/kg) | BEHAVIORAL: TREMOR BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: EXCITEMENT |
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 116, Pg. 17, 1958. |
Consensus Reports：
SAFETY PROFILE：
Poison by ingestion, intramuscular, and intraperitoneal routes. When ortho-Methylcyclizine dihydrochloride (CAS NO.24342-56-1) is heated to decomposition ,it emits toxic fumes of NOx and HCl.
Standards and Recommendations：
Analytical Methods：
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