CAS No.:532-62-7

TOXICITY DATA with REFERENCE：

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LDLo	intraperitoneal	82mg/kg (82mg/kg)		"Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 1, Pg. 308, 1955.
dog	LDLo	intravenous	15mg/kg (15mg/kg)		Physiological Reviews. Vol. 12, Pg. 190, 1932.
guinea pig	LDLo	intraperitoneal	250mg/kg (250mg/kg)		Physiological Reviews. Vol. 12, Pg. 190, 1932.
guinea pig	LDLo	intravenous	30mg/kg (30mg/kg)		Physiological Reviews. Vol. 12, Pg. 190, 1932.
guinea pig	LDLo	subcutaneous	193mg/kg (193mg/kg)		Physiological Reviews. Vol. 12, Pg. 190, 1932.
mouse	LDLo	intravenous	50mg/kg (50mg/kg)		Physiological Reviews. Vol. 12, Pg. 190, 1932.
mouse	LDLo	subcutaneous	350mg/kg (350mg/kg)		Physiological Reviews. Vol. 12, Pg. 190, 1932.
rabbit	LDLo	intraspinal	16mg/kg (16mg/kg)		Journal of Pharmacology and Experimental Therapeutics. Vol. 57, Pg. 221, 1936.
rabbit	LDLo	intravenous	15mg/kg (15mg/kg)		Physiological Reviews. Vol. 12, Pg. 190, 1932.
rabbit	LDLo	subcutaneous	200mg/kg (200mg/kg)		Physiological Reviews. Vol. 12, Pg. 190, 1932

Consensus Reports：

 

SAFETY PROFILE：

Poison by subcutaneous, intravenous, intraperitoneal, and intraspinal routes. When p-Aminobenzoyldimethylamino-1,2-dimethylpropanol hydrochloride (CAS NO.532-62-7) is heated to decomposition, it emits very toxic fumes of HCl and NO_x. Used as a surface and infiltration anesthetic.

Standards and Recommendations：

 

Analytical Methods：