CAS No.:1634-04-4

TOXICITY DATA with REFERENCE：

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LC50	inhalation	141gm/m3/15M (141000mg/m3)	BEHAVIORAL: GENERAL ANESTHETIC	Anesthesiology. Vol. 11, Pg. 455, 1950.
mouse	LD50	intraperitoneal	1700uL/kg (1.7mL/kg)		Zhonghua Yixue Zazhi. Chinese Medical Journal. Vol. 70, Pg. 172, 1990.
mouse	LD50	oral	5960uL/kg (5.96mL/kg)		Zhonghua Yixue Zazhi. Chinese Medical Journal. Vol. 70, Pg. 172, 1990.
rat	LC50	inhalation	23576ppm/4H (23576ppm)		National Technical Information Service. Vol. PB87-174603,
rat	LD	intraperitoneal	> 148mg/kg (148mg/kg)		Journal of Surgical Research. Vol. 53, Pg. 572, 1992.
rat	LD50	oral	4gm/kg (4000mg/kg)		National Technical Information Service. Vol. PB87-174603,
rat	LDLo	intravenous	148mg/kg (148mg/kg)		Journal of Surgical Research. Vol. 53, Pg. 572, 1992.

Consensus Reports：

Community Right-To-Know List. Reported in EPA TSCA Inventory.

SAFETY PROFILE：

Hazard Codes of tert-Butyl methyl ether (CAS NO.1634-04-4): Xn,F,XiT
Risk Statements: 36/37/38-40-11-39-23/24/25
R36/37/38: Irritating to eyes, respiratory system and skin. 
R40: Limited evidence of a carcinogenic effect. 
R11: Highly flammable. 
R39: Danger of very serious irreversible effects. 
R23/24/25: Toxic by inhalation, in contact with skin and if swallowed.
Safety Statements: 9-16-24-45-36/37 
S9: Keep container in a well-ventilated place. 
S16: Keep away from sources of ignition. 
S24: Avoid contact with skin. 
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) 
S36/37: Wear suitable protective clothing and gloves.
RIDADR: UN 2398 3/PG 2
WGK Germany: 3
RTECS: KN5250000
F: 3-10
HazardClass: 3
PackingGroup: II
Hazardous Substances Data: 1634-04-4(Hazardous Substances Data)
Poison by intravenous route. Slightly toxic by ingestion and inhalation. Flammable when exposed to heat or flame. When heated to decomposition it emits acrid smoke and irritating fumes. See also ETHERS.

Standards and Recommendations：

ACGIH TLV: TWA 50 ppm; Confirmed Animal Carcinogen with Unknown Revelance to Humans
DOT Classification:  3; Label: Flammable Liquid

Analytical Methods：

For occupational chemical analysis use NIOSH: tert-Butyl methyl ether (MTBE) 1615.