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NovoLog (insulin aspart) is a fast-acting form of insulin that works by lowering levels of glucose (sugar) in the blood.

NovoLog is used to treat type 1 (insulin-dependent) diabetes in adults and children who are at least 2 years old. NovoLog is usually given together with another long-acting insulin.

Important information

NovoLog is a fast-acting insulin that begins to work very quickly. After using it, you should eat a meal within 5 to 10 minutes.

Never share an injection pen or cartridge with another person. Sharing injection pens or cartridges can allow disease such as hepatitis or HIV to pass from one person to another.

Before taking this medicine

You should not use NovoLog if you are allergic to insulin, or if you are having an episode of hypoglycemia (low blood sugar).

To make sure NovoLog is safe for you, tell your doctor if you have:

  • liver or kidney disease; or

  • if you take any oral (taken by mouth) diabetes medicine.

FDA pregnancy category B. NovoLog is not expected to harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

See also: Pregnancy and breastfeeding warnings (in more detail)

It is not known whether insulin aspart passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

How should I use NovoLog?

Use NovoLog exactly as it was prescribed for you. Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.

NovoLog is given as an injection (shot) under your skin, using a needle and syringe or an insulin pump. You will be shown how to use injections at home. Do not self inject this medicine if you do not understand how to give the injection and properly dispose of used needles and syringes.

NovoLog is a fast-acting medicine that begins to work very quickly. After using NovoLog, you should eat a meal within 5 to 10 minutes.

Choose a different place in your injection skin area each time you use this medication. Do not inject into the same place two times in a row.

If you use this medicine with an insulin pump, do not mix or dilute NovoLog with any other insulin. Infusion pump tubing, catheters, and the needle location on your skin should be changed every 48 hours. Throw away any medication leftover in the reservoir.

Never share an injection pen or cartridge with another person. Sharing injection pens or cartridges can allow disease such as hepatitis or HIV to pass from one person to another.

Infusion pump tubing, catheters, and the needle location on your skin should be changed every 48 hours. Throw away any medicine leftover in the reservoir.

Follow any state or local laws about throwing away used needles and syringes. Use a puncture-proof "sharps" disposal container (ask your pharmacist where to get one and how to throw it away). Keep this container out of the reach of children and pets.

Your blood sugar will need to be checked often, and you may need other blood tests at your doctor"s office.

Low blood sugar (hypoglycemia) can happen to everyone who has diabetes. Symptoms include headache, hunger, sweating, confusion, irritability, dizziness, or feeling shaky. Always keep a source of sugar with you in case you have low blood sugar. Sugar sources include fruit juice, hard candy, crackers, raisins, and non-diet soda. Be sure your family and close friends know how to help you in an emergency.

If you have severe hypoglycemia and cannot eat or drink, use a glucagon injection. Your doctor can prescribe a glucagon emergency injection kit and tell you how to use it.

Also watch for signs of high blood sugar (hyperglycemia) such as increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision, and weight loss.

Check your blood sugar carefully during times of stress, travel, illness, surgery or medical emergency, vigorous exercise, or if you drink alcohol or skip meals. These things can affect your glucose levels and your dose needs may also change. Do not change your medication dose or schedule without your doctor"s advice.

NovoLog is only part of a treatment program that may also include diet, exercise, weight control, blood sugar testing, and special medical care. Follow your doctor"s instructions very closely.

Storing unopened vials, cartridges, or injection pens: Keep in the carton and store in a refrigerator, protected from light. Throw away any insulin not used before the expiration date on the medicine label.

Unopened vials, cartridges, or injection pens may also be stored at room temperature for up to 28 days, away from heat and bright light. Throw away any insulin not used within 28 days.

Storing after your first use: Keep the "in-use" vials, cartridges, or injection pens at room temperature and use within 28 days. Do not refrigerate.

Do not freeze NovoLog or expose it to high heat. Throw away the medicine if it has become frozen or if it becomes hotter than 98 degrees F.

What happens if I miss a dose?

Since NovoLog is used before meals, you may not be on a timed dosing schedule. Whenever you use this medicine, be sure to eat a meal within 5 to 10 minutes. Do not use extra to make up a missed dose.

It is important to keep NovoLog on hand at all times. Get your prescription refilled before you run out of medicine completely.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An insulin overdose can cause life-threatening hypoglycemia.

Symptoms of severe hypoglycemia include extreme weakness, blurred vision, sweating, trouble speaking, tremors, stomach pain, confusion, seizure (convulsions), or coma.

What should I avoid while using NovoLog?

Do not change the brand of insulin aspart or syringe you are using without first talking to your doctor or pharmacist.

Avoid drinking alcohol. It can lower your blood sugar while using NovoLog.

NovoLog side effects

Get emergency medical help if you have any of these signs of insulin allergy: itching skin rash over the entire body, wheezing, trouble breathing, fast heart rate, sweating, or feeling like you might pass out.

Call your doctor if you have a serious side effect such as:

  • swelling in your hands or feet; or

  • low potassium--confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, muscle weakness or limp feeling.

Common NovoLog side effects may include low blood sugar (headache, hunger, weakness, sweating, confusion, irritability, dizziness, fast heart rate, or feeling jittery).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

What other drugs will affect NovoLog?

Many other medicines can increase or decrease the effects of NovoLog on lowering your blood sugar. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.


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