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Current position:Home > Products > 1-(2-(2-(Diethylamino)ethoxy)phenyl)-3-phenyl-1-propanone hydrochloride

CAS No.:2192-21-4

Name: 1-(2-(2-(Diethylamino)ethoxy)phenyl)-3-phenyl-1-propanone hydrochloride

Details Introduction

TOXICITY DATA with REFERENCE:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 oral 50mg/kg (50mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Arzneimittel-Forschung. Drug Research. Vol. 19, Pg. 1664, 1969.
mouse LD50 intraperitoneal 90mg/kg (90mg/kg)   Drugs in Japan Vol. -, Pg. 180, 1990.
mouse LD50 intravenous 28mg/kg (28mg/kg)   Pharmaceutical Chemistry Journal Vol. 23, Pg. 966, 1989.
mouse LD50 oral 352mg/kg (352mg/kg)   Drugs in Japan Vol. 6, Pg. 109, 1982.
mouse LD50 subcutaneous 234mg/kg (234mg/kg)   Pharmaceutical Chemistry Journal Vol. 21, Pg. 646, 1987.
rat LD50 intraperitoneal 66mg/kg (66mg/kg)   Drugs in Japan Vol. -, Pg. 180, 1990.
rat LD50 intravenous 20800ug/kg (20.8mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Arzneimittel-Forschung. Drug Research. Vol. 19, Pg. 1664, 1969.
rat LD50 oral 716mg/kg (716mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Arzneimittel-Forschung. Drug Research. Vol. 19, Pg. 1664, 1969.
rat LD50 subcutaneous 1900mg/kg (1900mg/kg)   Drugs in Japan Vol. -, Pg. 180, 1990.


Consensus Reports:

 


SAFETY PROFILE:

Poison by ingestion and intravenous routes. When heated to decomposition it emits very toxic fumes of NOx and HCl.


Standards and Recommendations:

 


Analytical Methods:

 


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