CAS No.:759-73-9

TOXICITY DATA with REFERENCE：

1.		dni-hmn:hla 100 µmol/L		MUREAV    Mutation Research. 92 (1982),427.
2.		cyt-ham-orl 100 mg/kg		TRENAF    Kenkyu Nenpo-Tokyo-toritsu Eisei Kenkyusho. Annual Report of Tokyo Metropolitan Research Laboratory of Public Health. 36 (1985),396.
3.		orl-rat TDLo:10 mg/kg (female 19D post):NEO,TER		CALEDQ    Cancer Letters (Shannon, Ireland). 2 (1976),93.
4.		skn-rat TDLo:350 mg/kg (female 16-22D post):NEO,TER		ZEKBAI    Zeitschrift fuer Krebsforschung. 81 (1974),169.
5.		ipr-rat TDLo:10 mg/kg (female 15D post):NEO,TER		SCIEAS    Science. 218 (1982),682.
6.		ivn-rat TDLo:50 mg/kg (15D preg):CAR,TER		ZEKBAI    Zeitschrift fuer Krebsforschung. 73 (1970),371.
7.		unr-rat TDLo:5 mg/kg (13D preg):ETA,TER		XENOBH    Xenobiotica. 3 (1973),271.
8.		ipr-mus TDLo:20 mg/kg (19D preg):CAR,TER		VOONAW    Voprosy Onkologii. Problems of Onkology. 23 (3)(1977),41.
9.		par-mus TDLo:100 mg/kg/(18D preg):ETA,TER		PAACA3    Proceedings of the American Association for Cancer Research. 17 (1976),122.
10.		par-mus TDLo:58,565 µg/kg (18D preg):CAR,TER	&n

Consensus Reports：

NTP 10th Report on Carcinogens. IARC Cancer Review: Group 2A IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 (1987),p. 56.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Human Limited Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 17 (1978),p. 191.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Sufficient Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 17 (1978),p. 191.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 1 (1972),p. 135.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . EPA Genetic Toxicology Program. Community Right-To-Know List. Reported in EPA TSCA Inventory.

SAFETY PROFILE：

Confirmed carcinogen with experimental carcinogenic, neoplastigenic, tumorigenic, and teratogenic data. Poison by ingestion, subcutaneous, intraperitoneal, and intravenous routes. Human mutation data reported. When heated to decomposition it emits toxic fumes of NO_x. See also N-NITROSO COMPOUNDS.Safety information of 1-Ethyl-1-nitrosourea (CAS NO.759-73-9):
Hazard Codes  T
Risk Statements 
45 May cause cancer
46 May cause heritable genetic damage
61 May cause harm to the unborn child
20/21/22 Harmful by inhalation, in contact with skin and if swallowed
Safety Statements 
53 Avoid exposure - obtain special instruction before use
22 Do not breathe dust
36/37/39 Wear suitable protective clothing, gloves and eye/face protection
45 In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
RIDADR  UN 2811 6.1/PG 3
WGK Germany  3
RTECS  YT3150000
HazardClass  6.1(b)
PackingGroup  III

Standards and Recommendations：

 

Analytical Methods：