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Current position:Home > Products > 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride

CAS No.:23007-85-4

Name: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride

Details Introduction

TOXICITY DATA with REFERENCE:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 oral 150mg/kg (150mg/kg)   Annales Pharmaceutiques Francaises. Vol. 12, Pg. 241, 1954.
mouse LD50 subcutaneous 53800ug/kg (53.8mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS

BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)
Journal of Pharmacology and Experimental Therapeutics. Vol. 247, Pg. 531, 1988.
rat LD50 intraperitoneal 72mg/kg (72mg/kg) BEHAVIORAL: TREMOR

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)
Bulletin of Experimental Biology and Medicine Vol. 105, Pg. 470, 1988.

 


Consensus Reports:

 


SAFETY PROFILE:

A poison by intraperitoneal and subcutaneous routes. Experimental reproductive effects. When heated to decomposition it emits toxic vapors of NOx and Cl.
Hazard Codes ToxicT
Risk Statements 39-23/24/25
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed. 
R39:Danger of very serious irreversible effects.
Safety Statements 45
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR 2811
RTECS UT8358950
HazardClass 6.1(b)
PackingGroup III


Standards and Recommendations:

 


Analytical Methods:

 


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