CAS No.:93-76-5

TOXICITY DATA with REFERENCE：

1.		mmo-bcs 1 nmol/plate		MSERDS    Microbiology Series. 5 (1981),93.
2.		cyt-grb-ipr 250 mg/kg		MUREAV    Mutation Research. 65 (1979),83.
3.		orl-rat TDLo:6 mg/kg (female 8D post):REP		EXPEAM    Experientia. 39 (1983),891.
4.		orl-rat TDLo:100 mg/kg (female 11D post):TER		BEXBAN    Bulletin of Experimental Biology and Medicine. Translation of BEBMAE. 76 (1973),831.
5.		orl-mus TDLo:3379 mg/kg/33W-C:NEO		BJCAAI    British Journal of Cancer. 33 (1976),626.
6.		scu-mus TDLo:215 mg/kg:ETA		NTIS**    National Technical Information Service. (Springfield, VA 22161) (Formerly U.S. Clearinghouse for Scientific and Technical Information) PB223-159 .
7.		orl-rat LD50:300 mg/kg		RREVAH    Residue Reviews. 10 (1965),97.
8.		skn-rat LD50:1535 mg/kg		FAATDF    Fundamental and Applied Toxicology. 7 (1986),299.
9.		orl-mus LD50:242 mg/kg		RPZHAW    Roczniki Panstwowego Zakladu Higieny. 31 (1980),373.
10.		orl-dog LD50:100 mg/kg		PAREAQ    Pharmacological Reviews. 14 (1962),225.

Consensus Reports：

IARC Cancer Review: Group 2B IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 ,1987,p. 156.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Inadequate Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 15 ,1977,p. 273.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Human Inadequate

 

1.

Evidence ; Human Limited Evidence . Reported in EPA TSCA Inventory. EPA Genetic Toxicology Program.

IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 15 ,1977,p. 273.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 41 ,1986,p. 357.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210)

 
 

Standards and Recommendations:

 

OSHA PEL: TWA 10 mg/m³

 

ACGIH TLV: TWA 10 mg/m³; Not Classifiable as a Human Carcinogen

 

DFG MAK: 10 mg/m³

SAFETY PROFILE：

Poison by ingestion. Moderately toxic by skin contact. Questionable carcinogen with experimental neoplastigenic, tumorigenic, and teratogenic data. Experimental reproductive effects. Mutation data reported. A highly toxic chlorinated phenoxy acid herbicide that is rapidly excreted after ingestion. Readily absorbed by inhalation and ingestion routes, slowly by skin contact. Signs of intoxication include weakness, lethargy, anorexia, diarrhea, ventricular fibrillation and/or cardiac arrest, and death. The teratogenicity is due in part to 2,3,7,8-TCDD, which is present as a contaminant (ARENAA 17,123,72). When heated to decomposition it emits toxic fumes of Cl⁻. See also TCDD and CHLOROPHENOLS.Safety information of 2-(2,4,5-Trichlorophenoxy)acetic acid (CAS NO.93-76-5):
Hazard Codes  Xn,N,F
Risk Statements 
36/37/38 Irritating to eyes, respiratory system and skin
50/53 Very Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment
20/21/22 Harmful by inhalation, in contact with skin and if swallowed
11 Highly Flammable
Safety Statements 
24 Avoid contact with skin
60 This material and/or its container must be disposed of as hazardous waste
61 Avoid release to the environment. Refer to special instructions safety data sheet
36/37 Wear suitable protective clothing and gloves
26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
RIDADR  UN 2811 6.1/PG 3
WGK Germany  3
RTECS  AJ8400000
HazardClass  6.1(b)
PackingGroup  III

Standards and Recommendations：

OSHA PEL: TWA 10 mg/m³
ACGIH TLV: TWA 10 mg/m³; Not Classifiable as a Human Carcinogen
DFG MAK: 10 mg/m³

Analytical Methods：

For occupational chemical analysis use NIOSH: 2,4-D and 2,4,5-T, 5001.