CAS No.:137-17-7
Name: 2,4,5-Trimethylaniline
Details Introduction
TOXICITY DATA with REFERENCE:
1. |
mma-sat 10 µg/plate |
ENMUDM Environmental Mutagenesis. 8 (Suppl 7)(1986),1. | ||
2. |
dnd-ham:lng 10 mmol/L |
MUREAV Mutation Research. 77 (1980),317. | ||
3. |
orl-rat LD50:1250 mg/kg |
MarJV# Personal Communication from Josef V. Marhold, VUOS, 539-18, Pardubice, Czechoslovakia, to the Editor of RTECS, Cincinnati, OH, March 29, 1977 29MAR77 . |
Consensus Reports:
IARC Cancer Review: Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 ,1987,p. 56.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 27 ,1982,p. 177.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . NCI Carcinogenesis Bioassay (feed); Clear Evidence: mouse, rat NCITR* National Cancer Institute Carcinogenesis Technical Report Series. (Bethesda, MD 20014) No. NCI-CG-TR-160 ,1979. .
SAFETY PROFILE:
Safety Information of 2,4,5-Trimethylaniline (CAS NO.137-17-7):
Hazard Codes: F ,Xn ,N ,T
Hazard Note: Harmful
Risk Statements: 11-20/21/22-36-51/53-23/24/25-45
R11:Highly flammable
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed
R36:Irritating to eyes
R51/53:Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed
R45:May cause cancer
Safety Statements: 16-36/37-61-45-53
S16:Keep away from sources of ignition
S36/37:Wear suitable protective clothing and gloves
S61:Avoid release to the environment. Refer to special instructions / safety data sheets
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S53:Avoid exposure - obtain special instructions before use
RIDADR: UN1648 3/PG 2
RTECS: BZ0520000
Confirmed carcinogen with experimental carcinogenic and tumorigenic data. Moderately toxic by ingestion. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx. Used as a dye, pigment, and printing ink. See also ANILINE DYES.
Standards and Recommendations:
DFG MAK: Animal Carcinogen, Suspected Human Carcinogen
Analytical Methods:
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