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Current position:Home > Products > 2,4-Dichlorophenoxyacetic acid

CAS No.:94-75-7

Name: 2,4-Dichlorophenoxyacetic acid

Details Introduction

TOXICITY DATA with REFERENCE:

1.    

skn-rbt 500 mg/24H MLD

    28ZPAK    Sbornik Vysledku Toxixologickeho Vysetreni Latek A Pripravku Marhold, J.V.,Institut Pro Vychovu Vedoucicn Pracovniku Chemickeho Prumyclu Praha,Czechoslovakia.: 1972,279.
2.    

eye-rbt 750 μg/24H SEV

    28ZPAK    Sbornik Vysledku Toxixologickeho Vysetreni Latek A Pripravku Marhold, J.V.,Institut Pro Vychovu Vedoucicn Pracovniku Chemickeho Prumyclu Praha,Czechoslovakia.: 1972,279.
3.    

sce-hmn:lym 10 mg/L

    JOHEA8    Journal of Heredity. 73 (1982),224.
4.    

dni-ham:ovr 1 mmol/L

    TOLED5    Toxicology Letters. 29 (1985),137.
5.    

orl-rat TDLo:500 mg/kg (female 6-15D post):REP

    FCTXAV    Food and Cosmetics Toxicology. 9 (1971),801.
6.    

orl-mus TDLo:707 mg/kg (female 11-14D post):TER

    AECTCV    Archives of Environmental Contamination and Toxicology. 6 (1977),33.
7.    

orl-man TDLo:2 g/kg:BAH,PUL

    ARTODN    Archives of Toxicology. 66 (1992),518.
8.    

orl-man TDLo:5714 mg/kg:BAH,CVS

    ARTODN    Archives of Toxicology. 66 (1992),518.
9.    

orl-hmn LDLo:80 mg/kg:GIT,CNS

    ARPAAQ    Archives of Pathology. 94 (1972),270.
10.    

orl-ma


Consensus Reports:IARC Cancer Review: Group 2B IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 (1987),p. 156.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Human Limited Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 41 (1986),p. 357.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Inadequate Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 15 (1977),p. 111.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Human Inadequate Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 15 (1977),p. 111.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . EPA Genetic Toxicology Program. Reported in EPA TSCA Inventory. Community Right-To-Know List.
SAFETY PROFILE:
Suspected human carcinogen. Experimental teratogenic and reproductive effects. Poison by ingestion, intravenous, and intraperitoneal routes. Moderately toxic by skin contact. Human systemic effects by ingestion: change in heart rate, coma, convulsions, nausea or vomiting, respiratory depression, somnolence. Can cause liver and kidney injury. A skin and severe eye irritant. Human mutation data reported.
Standards and Recommendations:OSHA PEL: TWA 10 mg/m3
ACGIH TLV: TWA 10 mg/m3; Not Classifiable as a Human Carcinogen
DFG MAK: 1 mg/m3
Analytical Methods:For occupational chemical analysis use NIOSH: 2,4-D and 2,4,5-T, 5001.

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