CAS No.:6331-04-0

TOXICITY DATA with REFERENCE：

 

Consensus Reports：

 

SAFETY PROFILE：

Safty information about 2,5-Dimethylphenylacetic Acid (CAS NO.6331-04-0) :
Hazard Codes:
Xi: Irritant
Risk Statements:
R36/37/38:Irritating to eyes, respiratory system and skin. 
Safety Statements:
S37/39:Wear suitable gloves and eye/face protection.  
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

Standards and Recommendations：

 

Analytical Methods：

 2,5-Dimethylphenylacetic Acid can surprisingly be obtained in high yield and purity by initially converting p-xylene with chloroacetyl chloride in a Friedel-Crafts reaction into 2-chloro-1-(2,5-dimethylphenyl)ethanone of the formula (I) , preparing from this ketone with a diol of the general formula (II) the corresponding ketal of the general formula (III), then rearranging the latter to a mixture of the corresponding hydroxyalkyl 2,5-dimethylphenylacetates of the general formula (IV) and bis(2,5-dimethylphenylacetic acid) diesters of the general formula (V) , and finally hydrolyzing the latter to give 2,5-Dimethylphenylacetic Acid .