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CAS No.:109-09-1

Name: 2-Chloropyridine

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Details Introduction

TOXICITY DATA with REFERENCE:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
bird - wild LD50 oral 1gm/kg (1000mg/kg)   Archives of Environmental Contamination and Toxicology. Vol. 12, Pg. 355, 1983.
mouse LD50 intraperitoneal 130mg/kg (130mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: ANTIPSYCHOTIC

LIVER: FATTY LIVER DEGERATION
Toxicology and Applied Pharmacology. Vol. 11, Pg. 361, 1967.
mouse LD50 oral 110mg/kg (110mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: ANTIPSYCHOTIC

LIVER: OTHER CHANGES
Toxicology and Applied Pharmacology. Vol. 11, Pg. 361, 1967.
rabbit LD50 intraperitoneal 48mg/kg (48mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LIVER: FATTY LIVER DEGERATION

BEHAVIORAL: ANTIPSYCHOTIC
Toxicology and Applied Pharmacology. Vol. 11, Pg. 361, 1967.
rabbit LD50 skin 64mg/kg (64mg/kg) LIVER: OTHER CHANGES Toxicology and Applied Pharmacology. Vol. 11, Pg. 361, 1967.
rat LCLo inhalation 100ppm/4H (100ppm) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: ANTIPSYCHOTIC

LIVER: OTHER CHANGES
Toxicology and Applied Pharmacology. Vol. 11, Pg. 361, 1967.


Consensus Reports:

Reported in EPA TSCA Inventory.


SAFETY PROFILE:

Safty information about 2-Chloropyridine (CAS NO.109-09-1) is:
Poison by ingestion, inhalation, skin contact, and intraperitoneal routes. Combustible when exposed to heat or flame. Can react with oxidizing materials. When heated to decomposition it emits very toxic fumes of Cl, NOx, and phosgene.
Hazard Codes: ToxicT
Risk Statements: 23/24/25-36/37/38 
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed. 
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 26-36/37/39-45-28A-27 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection. 
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) 
S28:After contact with skin, wash immediately with plenty of soap-suds. 
S27:Take off immediately all contaminated clothing.
RIDADR: UN 2822 6.1/PG 2
WGK Germany: 3
RTECS: US5950000
Hazard Note: Toxic
HazardClass: 6.1
PackingGroup: II
HS Code: 29333999


Standards and Recommendations:

 


Analytical Methods:

 


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