CAS No.:78-80-8

TOXICITY DATA with REFERENCE：

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LC50	inhalation	12600mg/m3 (12600mg/m3)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 31(4), Pg. 55, 1987.
mouse	LD	intraperitoneal	> 500mg/kg (500mg/kg)		"Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. Vol. 8, Pg. 100, 1956.
mouse	LD50	oral	350mg/kg (350mg/kg)		Shell Chemical Company. Unpublished Report. Vol. -, Pg. 6, 1961.
rat	LDLo	oral	639mg/kg (639mg/kg)		Shell Chemical Company. Unpublished Report. Vol. -, Pg. 6, 1961.

Consensus Reports：

 

SAFETY PROFILE：

Poison by ingestion. Mildly toxic by inhalation. A skin irritant. A very dangerous fire hazard when exposed to heat or flame. When heated to decomposition it emits acrid smoke and irritating fumes. See also ACETYLENE COMPOUNDS and ALKYNES.
Safety Information of 2-Methyl-1-buten-3-yne (CAS NO.78-80-8):
Hazard Codes: F+,Xn,F,Xi
Risk Statements: 12-20/22-36/37/38-65 
12:  Extremely Flammable 
20:  Harmful by inhalation 
22:  Harmful if swallowed 
36:  Irritating to the eyes 
37:  Irritating to the respiratory system 
38:  Irritating to the skin 
65:  Harmful: May cause lung damage if swallowed 
Safety Statements: 16-26-36/37-62
16:  Keep away from sources of ignition - No smoking 
26:  In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 
36:  Wear suitable protective clothing  
37:  Wear suitable gloves 
62:  If swallowed, do not induce vomiting: seek medical advice immediately and show this container or label 

Standards and Recommendations：

 

Analytical Methods：