CAS No.:555-29-3
Name: 3-Hydroxy-alpha-methyl-DL-tyrosine
Details Introduction
TOXICITY DATA with REFERENCE:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intraperitoneal | 1317mg/kg (1317mg/kg) | LIVER: "HEPATITIS (HEPATOCELLULAR NECROSIS), DIFFUSE" KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)" |
Journal of Medicinal Chemistry. Vol. 23, Pg. 1318, 1980. |
mouse | LD50 | intravenous | 1760mg/kg (1760mg/kg) | National Toxicology Program Technical Report Series. Vol. NTP-TR-348, Pg. 1989, | |
mouse | LD50 | oral | 5370mg/kg (5370mg/kg) | National Toxicology Program Technical Report Series. Vol. NTP-TR-348, Pg. 1989, | |
rat | LD50 | intraperitoneal | 430mg/kg (430mg/kg) | National Toxicology Program Technical Report Series. Vol. NTP-TR-348, Pg. 1989, | |
rat | LD50 | oral | 5710mg/kg (5710mg/kg) | National Toxicology Program Technical Report Series. Vol. NTP-TR-348, Pg. 1989, |
Consensus Reports:
SAFETY PROFILE:
Hazard Codes:
Xi: Irritant
Risk Statements about DL-Methyldopa (555-29-3):
R36 Irritating to eyes.
Safety Statements about DL-Methyldopa (555-29-3):
S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37: Wear suitable protective clothing and gloves.
Standards and Recommendations:
Analytical Methods:
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