CAS No.:119-34-6

TOXICITY DATA with REFERENCE：

1.		eye-rbt 100 mg/24H SEV		28ZPAK    Sbornik Vysledku Toxixologickeho Vysetreni Latek A Pripravku Marhold, J.V.,Institut Pro Vychovu Vedoucicn Pracovniku Chemickeho Prumyclu Praha,Czechoslovakia.: 1972,107.
2.		mma-sat 100 µg/plate		IAPUDO    IARC Publications. 27 (1980),283.
3.		eye-rbt 100 mg/24H SEV		28ZPAK    Sbornik Vysledku Toxixologickeho Vysetreni Latek A Pripravku Marhold, J.V.,Institut Pro Vychovu Vedoucicn Pracovniku Chemickeho Prumyclu Praha,Czechoslovakia.: 1972,107.
4.		mmo-sat 100 µg/plate		ENMUDM    Environmental Mutagenesis. 8 (Suppl 5)(1985),1.
5.		otr-rat:emb 11 µg/plate		JJATDK    JAT, Journal of Applied Toxicology. 1 (1981),190.
6.		orl-rat LD50:1470 mg/kg		NCILB*    Progress Report for Contract No. NIH-NCI-E-C-72-3252, Submitted to the National Cancer Institute by Litton Bionetics, Inc. (Bethesda, MD) NIH-NCI-E-C-72-3252 ,1973.
7.		ipr-rat LD50:302 mg/kg		JTEHD6    Journal of Toxicology and Environmental Health. 2 (1977),657.
8.		orl-mus LD50:1470 mg/kg		NCILB*    Progress Report for Contract No. NIH-NCI-E-C-72-3252, Submitted to the National Cancer Institute by Litton Bionetics, Inc. (Bethesda, MD) NIH-NCI-E-C-72-3252 ,1973.

Consensus Reports：

IARC Cancer Review: Group 3 IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 ,1987,p. 56.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Inadequate Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 16 ,1978,p. 43.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . NCI Carcinogenesis Bioassay (feed); No Evidence: mouse NCITR*    National Cancer Institute Carcinogenesis Technical Report Series. (Bethesda, MD 20014) No. NCI-CG-TR-94 ,1978. ; Clear Evidence: rat NCITR*    National Cancer Institute Carcinogenesis Technical Report Series. (Bethesda, MD 20014) No. NCI-CG-TR-94 ,1978. . Reported in EPA TSCA Inventory. EPA Genetic Toxicology Program.

SAFETY PROFILE：

Suspected carcinogen with experimental carcinogenic data. Very poisonous by intraperitoneal route. Moderately toxic by ingestion. A severe eye irritant. Mutation data reported. When heated to decomposition it emits toxic fumes of NO_x.
Safety information of  2-Nitro-4-aminophenol (CAS NO.119-34-6):
Hazard Codes: Xn,T
Risk Statements:
22: Harmful if swallowed
36/37/38: Irritating to eyes, respiratory system and skin
45: May cause cancer
Safety Statements:
22: Do not breathe dust
24/25: Avoid contact with skin and eyes
37/39: Wear suitable gloves and eye/face protection
26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
53: Avoid exposure - obtain special instruction before use
45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
RIDADR: UN 2811 6.1/PG 3
WGK Germany: 3
RTECS: SJ6303000

Standards and Recommendations：

DFG MAK: Confirmed Animal Carcinogen with Unknown Relevance to Humans

Analytical Methods：