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Current position:Home > Products > Acetone cyanohydrin

CAS No.:75-86-5

Name: Acetone cyanohydrin

Details Introduction

TOXICITY DATA with REFERENCE:

1.    

orl-rat LD50:19,300 µg/kg

    GISAAA    Gigiena i Sanitariya. 58 (1)(1993),28.
2.    

ihl-rat LCLo:63 ppm/4H

    AIHAAP    American Industrial Hygiene Association Journal. 23 (1962),95.
3.    

scu-rat LDLo:8500 µg/kg

    BJIMAG    British Journal of Industrial Medicine. 19 (1962),283.
4.    

orl-mus LD50:14 mg/kg

    28ZPAK    Sbornik Vysledku Toxixologickeho Vysetreni Latek A Pripravku Marhold, J.V.,Institut Pro Vychovu Vedoucicn Pracovniku Chemickeho Prumyclu Praha,Czechoslovakia.: 1972,161.
5.    

ihl-mus LCLo:500 mg/m3/2H

    IGIBA5    Igiena. 11 (1962),27.
6.    

ipr-mus LD50:1 mg/kg

    NTIS**    National Technical Information Service. (Springfield, VA 22161) (Formerly U.S. Clearinghouse for Scientific and Technical Information) No. AD277-689 .
7.    

orl-rbt LD50:13,500 µg/kg

    NTIS**    National Technical Information Service. (Springfield, VA 22161) (Formerly U.S. Clearinghouse for Scientific and Technical Information) No. PB214-270 .
8.    

skn-rbt LD50:17 mg/kg

    AIHAAP    American Industrial Hygiene Association Journal. 23 (1962),95.
9.    

unr-rat TDLo:242 mg/kg/26W-I

    GISAAA    Gigiena i Sanitariya. 31 (6)(1966),8.
10.
  
Consensus Reports:Cyanide and its compounds are on the Community Right-To-Know List. Reported in EPA TSCA Inventory. EPA Extremely Hazardous Substances List.
SAFETY PROFILE:
Poison by ingestion, skin contact, inhalation, intraperitoneal, and subcutaneous routes. Readily decomposes to HCN and acetone. Keep cool and do not store for long periods. Combustible when exposed to heat or flame. To fight fire, use CO2, dry chemical, alcohol foam. Vigorous reaction with H2SO4. When heated to decomposition it emits toxic fumes of CN. See also NITRILES, HYDROCYANIC ACID, and ACETONE.
Standards and Recommendations:ACGIH TLV: CL 4.7 ppm (skin)
NIOSH REL: (Nitriles) CL 4 mg/m3/15M
DOT Classification:  6.1; Label: Poison
Analytical Methods:For occupational chemical analysis use NIOSH: Acetone Cyanohydrin, 2506.

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