CAS No.:134-80-5
Name: Amfepramone hydrochloride
Details Introduction
TOXICITY DATA with REFERENCE：
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intraperitoneal | 160mg/kg (160mg/kg) | Therapie. Vol. 17, Pg. 373, 1962. | |
| mouse | LD50 | intravenous | 50mg/kg (50mg/kg) | Acta Pharmacologica et Toxicologica. Vol. 17, Pg. 182, 1960. | |
| mouse | LD50 | oral | 385mg/kg (385mg/kg) | Therapie. Vol. 17, Pg. 373, 1962. | |
| mouse | LD50 | subcutaneous | 450mg/kg (450mg/kg) | sense organs and special senses: mydriasis (pupillary dilation): eye behavioral: excitement skin and appendages (skin): hair: other | Acta Pharmaceutica Suecica. Vol. 4, Pg. 37, 1967. |
| rat | LD50 | intraperitoneal | 139mg/kg (139mg/kg) | behavioral: excitement | Acta Pharmacologica et Toxicologica. Vol. 17, Pg. 121, 1960. |
| rat | LD50 | oral | 400mg/kg (400mg/kg) | Therapie. Vol. 17, Pg. 373, 1962. |
Consensus Reports：
SAFETY PROFILE：
Poison by intraperitoneal and intravenous routes. Moderately toxic by ingestion and subcutaneous routes. When heated to decomposition it emits very toxic fumes of HCl, NH3, and NOx.
Standards and Recommendations：
Analytical Methods：
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