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Current position:Home > Products > Bethanechol

CAS No.:590-63-6

Name: Bethanechol

Details Introduction

TOXICITY DATA with REFERENCE:

1.    

scu-hmn TDLo:130 mg/kg:SKN

    34ZIAG    Toxicology of Drugs and Chemicals ,Deichmann, W.B.,New York, NY.: Academic Press, Inc.,1969,130.
2.    

scu-man TDLo:1071 µg/kg/3D-I:SKN

    ARDEAC    Archives of Dermatology. 95 (1967),499.
3.    

orl-rat LD50:1500 mg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 58 (1936),337.
4.    

scu-rat LD50:175 mg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 58 (1936),337.
5.    

ivn-rat LD50:21 mg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 58 (1936),337.
6.    

ims-rat LD50:220 mg/kg

    NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),139.
7.    

orl-mus LD50:250 mg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 58 (1936),337.
8.    

scu-mus LD50:120 mg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 58 (1936),337.
9.    

ivn-mus LD50:10 mg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 58 (1936),337.
10.    

ims-mus LD50:192 


Consensus Reports:

Reported in EPA TSCA Inventory.


SAFETY PROFILE:

Poison by ingestion, subcutaneous, intramuscular and intravenous routes. Human systemic effects by subcutaneous route: allergic dermatitis and sweating. Used as a synthetic cholinergic drug. When heated to decomposition it emits very toxic fumes of NH3, NOx, and Cl. See also CARBAMATES.
Hazard Codes:
Xn: Harmful
Risk Statements about (2-Hydroxypropyl)trimethylammonium chloride carbamate (590-63-6):
R22 Harmful if swallowed.
Safety Statements about (2-Hydroxypropyl)trimethylammonium chloride carbamate (590-63-6):
S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.


Standards and Recommendations:

 


Analytical Methods:

 


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