CAS No.:7726-95-6
Name: Bromine
Details Introduction
TOXICITY DATA with REFERENCE:
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| guinea pig | LD50 | oral | 5500mg/kg (5500mg/kg) | Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 35(11), Pg. 11, 1970. | |
| human | LCLo | inhalation | 1000ppm (1000ppm) | "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 645, 1969. | |
| human | LDLo | oral | 14mg/kg (14mg/kg) | "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 645, 1969. | |
| mammal (species unspecified) | LD50 | oral | 440mg/kg (440mg/kg) | Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 39(4), Pg. 86, 1974. | |
| mouse | LC50 | inhalation | 750ppm/9M (750ppm) | American Industrial Hygiene Association Journal. Vol. 39, Pg. 129, 1978. | |
| mouse | LD50 | oral | 3100mg/kg (3100mg/kg) | Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 35(11), Pg. 11, 1970. | |
| rabbit | LCLo | inhalation | 180ppm/6.5H (180ppm) | "Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 1, Pg. 324, 1955. | |
| rabbit | LD50 | oral | 4160mg/kg (4160mg/kg) | Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 35(11), Pg. 11, 1970. | |
| rat | LC50 | inhalation | 2700mg/m3 (2700mg/m3) | LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES | Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 20(3), Pg. 36, 1976. |
| rat | LD50 | oral | 2600mg/kg (2600mg/kg) | Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 35(11), Pg. 11, 1970. |
Consensus Reports:
SAFETY PROFILE:
Hazard Codes:
T+
C,
N,T
Risk Statements: 26-35-50-40-22-46-45
R26: Very toxic by inhalation.
R35: Causes severe burns.
R50: Very toxic to aquatic organisms.
R40: Limited evidence of a carcinogenic effect.
R22: Harmful if swallowed.
R46: May cause heritable genetic damage.
R45: May cause cancer.
Safety Statements: 26-45-61-7/9-36/37/39-28-53
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S61: Avoid release to the environment. Refer to special instructions / safety data sheets.
S7: Keep container tightly closed.
S9: Keep container in a well-ventilated place.
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection.
S28: After contact with skin, wash immediately with plenty of soap-suds.
S53: Avoid exposure - obtain special instructions before use.
RIDADR: UN 1744 8/PG 1
WGK Germany: 2
RTECS: EF9100000
HazardClass: 8
PackingGroup: I
Hazardous Substances Data: 7726-95-6(Hazardous Substances Data)
Care needs to be taken when transporting bromine; it is commonly carried in steel tanks lined with lead, supported by strong metal frames.
When certain ionic compounds containing bromine are mixed with potassium permanganate (KMnO4) and an acidic substance, they will form a pale brown cloud of bromine gas. This gas smells like bleach and is very irritating to the mucus membranes. Upon exposure, one should move to fresh air immediately. If symptoms arise, medical attention is needed.
Standards and Recommendations:
Analytical Methods:
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