CAS No.:137-08-6

TOXICITY DATA with REFERENCE：

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	920mg/kg (920mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	Proceedings of the Society for Experimental Biology and Medicine. Vol. 45, Pg. 311, 1940.
mouse	LD50	intravenous	910mg/kg (910mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	Proceedings of the Society for Experimental Biology and Medicine. Vol. 45, Pg. 311, 1940.
mouse	LD50	oral	10gm/kg (10000mg/kg)		Drugs in Japan Vol. 6, Pg. 599, 1982.
mouse	LD50	subcutaneous	2700mg/kg (2700mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	Proceedings of the Society for Experimental Biology and Medicine. Vol. 45, Pg. 311, 1940.
rat	LD50	intraperitoneal	820mg/kg (820mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	Proceedings of the Society for Experimental Biology and Medicine. Vol. 45, Pg. 311, 1940.
rat	LD50	intravenous	830mg/kg (830mg/kg)		Drugs in Japan Vol. 6, Pg. 599, 1982.
rat	LD50	oral	> 10gm/kg (10000mg/kg)		Drugs in Japan Vol. 6, Pg. 599, 1982.
rat	LD50	subcutaneous	3400mg/kg (3400mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	Proceedings of the Society for Experimental Biology and Medicine. Vol. 45, Pg. 311, 1940

RTECS  RU4375000

Consensus Reports：

 

SAFETY PROFILE：

Hazard Codes: Xn
Risk Statements: 20/21/22-37/38-41-48 
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed. 
R37/38:Irritating to respiratory system and skin. 
R41:Risk of serious damage to the eyes. 
R48:Danger of serious damage to health by prolonged exposure.
Safety Statements: 24/25-45-36/37/39-26-22
S24/25:Avoid contact with skin and eyes. 
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) 
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection. 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S22:Do not breathe dust.
WGK Germany: 1
RTECS: RU4375000
F: 3-10

Standards and Recommendations：

 

Analytical Methods：