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Current position:Home > Products > Chlorpyrifos

CAS No.:2921-88-2

Name: Chlorpyrifos

Details Introduction

TOXICITY DATA with REFERENCE:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
bird - wild LD50 oral 5mg/kg (5mg/kg)   Toxicology and Applied Pharmacology. Vol. 21, Pg. 315, 1972.
chicken LD50 oral 25400ug/kg (25.4mg/kg) PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE)
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Toxicology and Applied Pharmacology. Vol. 11, Pg. 49, 1967.
duck LD50 oral 76mg/kg (76mg/kg)   Toxicology and Applied Pharmacology. Vol. 20, Pg. 57, 1971.
guinea pig LD50 oral 504mg/kg (504mg/kg)   Farm Chemicals Handbook. Vol. -, Pg. C74, 1991.
guinea pig LDLo subcutaneous 100mg/kg (100mg/kg)   Journal of Economic Entomology. Vol. 60, Pg. 733, 1967.
mammal (species unspecified) LD50 unreported 163mg/kg (163mg/kg)   Journal of Agricultural and Food Chemistry. Vol. 27, Pg. 712, 1979.
man TDLo oral 300mg/kg (300mg/kg) PERIPHERAL NERVE AND SENSATION: PARESTHESIS
BEHAVIORAL: MUSCLE WEAKNESS
BEHAVIORAL: COMA
Archives of Toxicology. Vol. 59, Pg. 176, 1986.
mouse LD50 intraperitoneal 192mg/kg (192mg/kg)   Toxicology and Applied Pharmacology. Vol. 65, Pg. 144, 1982.
mouse LD50 oral 60mg/kg (60mg/kg)   Journal of Environmental Science and Health, Part B: Pesticides, Food Contaminants, and Agricultural Wastes. Vol. 13, Pg. 11, 1978.
mouse LD50 skin 120mg/kg (120mg/kg)   Yakkyoku. Pharmacy. Vol. 38, Pg. 745, 1987.
pigeon LD50 oral 10mg/kg (10mg/kg)   ASTM Special Technical Publication. Vol. (680), Pg. 157, 1979.
quail LD50 oral 13300ug/kg (13.3mg/kg)   ASTM Special Technical Publication. Vol. (680), Pg. 157, 1979.
rabbit LD50 oral 1gm/kg (1000mg/kg)   Special Publication of the Entomological Society of America. Vol. 78-1, Pg. 45, 1978.
rabbit LD50 skin 2gm/kg (2000mg/kg)   Guide to the Chemicals Used in Crop Protection. Vol. 6, Pg. 203, 1973.
rat LC50 inhalation > 200mg/m3/4H (200mg/m3)   Pesticide Manual. Vol. 9, Pg. 166, 1991.
rat LD50 oral 82mg/kg (82mg/kg)   Toxicology and Applied Pharmacology. Vol. 14, Pg. 515, 1969.
rat LD50 skin 202mg/kg (202mg/kg)   Toxicology and Applied Pharmacology. Vol. 14, Pg. 515, 1969.
rat LD50 unreported 150mg/kg (150mg/kg)   "Chemistry of Pesticides," Melnikov, N.N., New York, Springer-Verlag New York, Inc., 1971Vol. -, Pg. 339, 1971.


Consensus Reports:

 


SAFETY PROFILE:

Hazard Symbols: ToxicT;Dangerous
Risk Codes: R25;R50/53
R25 :Toxic if swallowed. 
R50/53:Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.  
Safety Description: S1/2;S45;S60;S61
S1/2:Keep locked up and out of the reach of children. 
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) 
S60:This material and its container must be disposed of as hazardous waste. 
S61:Avoid release to the environment. Refer to special instructions / safety data sheets.


Standards and Recommendations:

 


Analytical Methods:

 


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