CAS No.:55870-43-4
Name: Coenzyme Q10
Details Introduction
TOXICITY DATA with REFERENCE：
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD | intramuscular | > 500mg/kg (500mg/kg) | BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) |
Oyo Yakuri. Pharmacometrics. Vol. 6, Pg. 769, 1972. |
| mouse | LD | intravenous | > 500mg/kg (500mg/kg) | BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA |
Oyo Yakuri. Pharmacometrics. Vol. 6, Pg. 769, 1972. |
| mouse | LD | oral | > 4gm/kg (4000mg/kg) | BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) |
Oyo Yakuri. Pharmacometrics. Vol. 6, Pg. 769, 1972. |
| mouse | LD | subcutaneous | > 500mg/kg (500mg/kg) | BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) |
Oyo Yakuri. Pharmacometrics. Vol. 6, Pg. 769, 1972. |
| rat | LD | intramuscular | > 500mg/kg (500mg/kg) | BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) |
Oyo Yakuri. Pharmacometrics. Vol. 6, Pg. 769, 1972. |
| rat | LD | intravenous | > 250mg/kg (250mg/kg) | BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA |
Oyo Yakuri. Pharmacometrics. Vol. 6, Pg. 769, 1972. |
| rat | LD | oral | > 4gm/kg (4000mg/kg) | BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) |
Oyo Yakuri. Pharmacometrics. Vol. 6, Pg. 769, 1972. |
| rat | LD | subcutaneous | > 500mg/kg (500mg/kg) | BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) |
Oyo Yakuri. Pharmacometrics. Vol. 6, Pg. 769, 1972. |
Consensus Reports：
SAFETY PROFILE：
Standards and Recommendations：
Analytical Methods：
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