CAS No.:54910-89-3

TOXICITY DATA with REFERENCE：

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
man	TDLo	oral	17mg/kg (17mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	American Journal of Emergency Medicine. Vol. 16, Pg. 328, 1998.
man	TDLo	oral	17mg/kg (17mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS" BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	American Journal of Emergency Medicine. Vol. 16, Pg. 328, 1998.
mouse	LD50	intraperitoneal	87500ug/kg (87.5mg/kg)		Drugs of the Future. Vol. 15, Pg. 1178, 1990.
mouse	LD50	oral	464mg/kg (464mg/kg)		Drugs of the Future. Vol. 15, Pg. 1178, 1990.
rat	LD50	intraperitoneal	121mg/kg (121mg/kg)		Drugs of the Future. Vol. 15, Pg. 1178, 1990.
rat	LD50	oral	825mg/kg (825mg/kg)		Drugs of the Future. Vol. 15, Pg. 1178, 1990.
women	TDLo	oral	2mg/kg/5D-I (2mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Archives of Internal Medicine. Vol. 156, Pg. 681, 1996.
women	TDLo	oral	16800ug/kg/6W (16.8mg/kg)	BEHAVIORAL: MUSCLE WEAKNESS BEHAVIORAL: ANTIPSYCHOTIC	Archives of Internal Medicine. Vol. 156, Pg. 681, 1996.
women	TDLo	oral	60mg/kg/21W-I (60mg/kg)		American Journal of Psychiatry. Vol. 153, Pg. 134, 1996.
women	TDLo	oral	72mg/kg/26W-I (72mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)	Journal of Clinical Pyschopharmacology. Vol. 10, Pg. 343, 1990.

Consensus Reports：

 

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Analytical Methods：