CAS No.:5002-47-1
Name: Fluphenazine decanoate
Details Introduction
TOXICITY DATA with REFERENCE:
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| dog | LD50 | intramuscular | > 1500mg/kg (1500mg/kg) | Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 35, Pg. 799, 1993. | |
| human | TDLo | intramuscular | 179ug/kg (0.179mg/kg) | BEHAVIORAL: ANTIPSYCHOTIC | American Journal of Psychiatry. Vol. 121, Pg. 784, 1965. |
| man | TDLo | intramuscular | 1071ug/kg/12D (1.071mg/kg) | BEHAVIORAL: ATAXIA SKIN AND APPENDAGES (SKIN): SWEATING: OTHER LUNGS, THORAX, OR RESPIRATION: DYSPNEA |
Annals of Emergency Medicine. Vol. 16, Pg. 705, 1987. |
| man | TDLo | intramuscular | 46mg/kg/5Y-I (46mg/kg) | BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) | British Journal of Psychiatry. Vol. 149, Pg. 524, 1986. |
| mouse | LD50 | intramuscular | 60mg/kg (60mg/kg) | SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) SKIN AND APPENDAGES (SKIN): HAIR: OTHER |
Jitchuken Zenrinsho Kenkyuho. Central Institute for Experimental Animals, Research Reports. Vol. 16, Pg. 87, 1990. |
| rat | LD50 | intramuscular | 576mg/kg (576mg/kg) | SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) SKIN AND APPENDAGES (SKIN): HAIR: OTHER |
Jitchuken Zenrinsho Kenkyuho. Central Institute for Experimental Animals, Research Reports. Vol. 16, Pg. 75, 1990. |
| rat | LD50 | oral | 19mg/kg (19mg/kg) | SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION |
Jitchuken Zenrinsho Kenkyuho. Central Institute for Experimental Animals, Research Reports. Vol. 16, Pg. 75, 1990. |
| women | TDLo | intramuscular | 21mg/kg/6D-I (21mg/kg) | CARDIAC: PULSE RATE GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS |
British Medical Journal. Vol. 286, Pg. 1016, 1983. |
Consensus Reports:
SAFETY PROFILE:
Safety information of Fluphenazine decanoate (5002-47-1):
RIDADR 3249
HazardClass 6.1(a)
PackingGroup II
Standards and Recommendations:
Analytical Methods:
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