CAS No.:110-00-9
Name: Furan
Details Introduction
TOXICITY DATA with REFERENCE:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
dog | LDLo | intravenous | 140mg/kg (140mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BLOOD: HEMORRHAGE |
Journal of Pharmacology and Experimental Therapeutics. Vol. 26, Pg. 281, 1926. |
dog | LDLo | oral | 234mg/kg (234mg/kg) | GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS GASTROINTESTINAL: NAUSEA OR VOMITING BLOOD: HEMORRHAGE |
Journal of Pharmacology and Experimental Therapeutics. Vol. 26, Pg. 281, 1926. |
mouse | LC50 | inhalation | 120mg/m3/1H (120mg/m3) | LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES |
American Industrial Hygiene Association Journal. Vol. 40, Pg. 310, 1979. |
mouse | LD50 | intraperitoneal | 7mg/kg (7mg/kg) | American Industrial Hygiene Association Journal. Vol. 40, Pg. 310, 1979. | |
rabbit | LDLo | oral | 234mg/kg (234mg/kg) | GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS GASTROINTESTINAL: NAUSEA OR VOMITING BLOOD: HEMORRHAGE |
Journal of Pharmacology and Experimental Therapeutics. Vol. 26, Pg. 281, 1926. |
rat | LC50 | inhalation | 3398ppm/1H (3398ppm) | SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA |
Hazelton Laboratories, Reports. Vol. HLA468-102, Pg. 1987, |
rat | LD50 | intraperitoneal | 5200ug/kg (5.2mg/kg) | American Industrial Hygiene Association Journal. Vol. 40, Pg. 310, 1979. |
Consensus Reports:
SAFETY PROFILE:
Hazard Codes of Furan (CAS NO.110-00-9): T,F+
Risk Statements: 45-12-19-20/22-38-48/22-52/53-68
R45: May cause cancer.
R12: Extremely flammable.
R19: May form explosive peroxides.
R20/22: Harmful by inhalation and if swallowed.
R38: Irritating to skin.
R48/22: Harmful: danger of serious damage to health by prolonged exposure if swallowed.
R52/53: Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
R68: Possible risk of irreversible effects.
Safety Statements: 53-45-61
S53: Avoid exposure - obtain special instructions before use.
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S61: Avoid release to the environment. Refer to special instructions / safety data sheets.
RIDADR: UN 2811 6.1/PG 2
WGK Germany: 3
RTECS: OB3870000
F: 8-9-23
HazardClass: 3
PackingGroup: I
Standards and Recommendations:
Analytical Methods:
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