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CAS No.:110-00-9

Name: Furan

Details Introduction

TOXICITY DATA with REFERENCE:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LDLo intravenous 140mg/kg (140mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BLOOD: HEMORRHAGE
Journal of Pharmacology and Experimental Therapeutics. Vol. 26, Pg. 281, 1926.
dog LDLo oral 234mg/kg (234mg/kg) GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS

GASTROINTESTINAL: NAUSEA OR VOMITING

BLOOD: HEMORRHAGE
Journal of Pharmacology and Experimental Therapeutics. Vol. 26, Pg. 281, 1926.
mouse LC50 inhalation 120mg/m3/1H (120mg/m3) LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
American Industrial Hygiene Association Journal. Vol. 40, Pg. 310, 1979.
mouse LD50 intraperitoneal 7mg/kg (7mg/kg)   American Industrial Hygiene Association Journal. Vol. 40, Pg. 310, 1979.
rabbit LDLo oral 234mg/kg (234mg/kg) GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS

GASTROINTESTINAL: NAUSEA OR VOMITING

BLOOD: HEMORRHAGE
Journal of Pharmacology and Experimental Therapeutics. Vol. 26, Pg. 281, 1926.
rat LC50 inhalation 3398ppm/1H (3398ppm) SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Hazelton Laboratories, Reports. Vol. HLA468-102, Pg. 1987,
rat LD50 intraperitoneal 5200ug/kg (5.2mg/kg)   American Industrial Hygiene Association Journal. Vol. 40, Pg. 310, 1979.


Consensus Reports:

 


SAFETY PROFILE:

Hazard Codes of Furan (CAS NO.110-00-9): ToxicT,HighlyF+
Risk Statements: 45-12-19-20/22-38-48/22-52/53-68 
R45: May cause cancer. 
R12: Extremely flammable. 
R19: May form explosive peroxides. 
R20/22: Harmful by inhalation and if swallowed. 
R38: Irritating to skin. 
R48/22: Harmful: danger of serious damage to health by prolonged exposure if swallowed. 
R52/53: Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment. 
R68: Possible risk of irreversible effects.
Safety Statements: 53-45-61 
S53: Avoid exposure - obtain special instructions before use. 
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) 
S61: Avoid release to the environment. Refer to special instructions / safety data sheets. 
RIDADR: UN 2811 6.1/PG 2
WGK Germany: 3
RTECS: OB3870000
F: 8-9-23
HazardClass: 3
PackingGroup: I


Standards and Recommendations:

 


Analytical Methods:

 


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