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Current position:Home > Products > Hydroxyzine

CAS No.:68-88-2

Name: Hydroxyzine

Details Introduction

TOXICITY DATA with REFERENCE:

1.    

orl-rat LD50:840 mg/kg

    CHTPBA    Chimica Therapeutica. 3 (1968),210.
2.    

ipr-rat LD50:160 mg/kg

    CHTPBA    Chimica Therapeutica. 3 (1968),210.
3.    

ivn-rat LD50:45 mg/kg

    ANPBAZ    Acta Neurologia et Psychiatrica Belgica. 61 (1961),669.
4.    

orl-mus LD50:480 mg/kg AANEAB 7,87,63

5.    

ipr-mus LD50:81,300 µg/kg

    DPHFAK    Dissertationes Pharmaceuticae et Pharmacologicae. 23 (1971),281.
6.    

ivn-mus LD50:137 mg/kg

    27ZQAG    Psychotropic Drugs and Related Compounds E. Usdin andD.H. Efron,2nd ed.,Washington, DC.: 1972,237.

Consensus Reports:

 


SAFETY PROFILE:

Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion. Experimental teratogenic and reproductive effects. When heated to decomposition it emits very toxic fumes of Cl and NOx.
Attentions:
1. Storage: Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
2. Handling: All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
 


Standards and Recommendations:

 


Analytical Methods:

 


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