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Current position:Home > Products > Isopropylamine

CAS No.:75-31-0

Name: Isopropylamine

Details Introduction

TOXICITY DATA with REFERENCE:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LD50 oral 2700mg/kg (2700mg/kg)   Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 45(3), Pg. 79, 1980.
mammal (species unspecified) LC50 inhalation 1800mg/m3 (1800mg/m3)   Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. Vol. 14, Pg. 80, 1975.
mammal (species unspecified) LD50 unreported 500mg/kg (500mg/kg)   Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. Vol. 14, Pg. 80, 1975.
mouse LCLo inhalation 7000ppm/40M (7000ppm)   Shell Chemical Company. Unpublished Report. Vol. -, Pg. 7, 1961.
mouse LD50 oral 2200mg/kg (2200mg/kg)   Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 45(3), Pg. 79, 1980.
rabbit LD50 oral 3200mg/kg (3200mg/kg) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"

SKIN AND APPENDAGES (SKIN): HAIR: OTHER
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 45(3), Pg. 79, 1980.
rabbit LD50 skin 380mg/kg (380mg/kg)   Interagency Collaborative Group on Environmental Carcinogenesis, National Cancer Institute, Memorandum, June 17, 1974Vol. 17JUN1974,
rat LC50 inhalation 4000ppm/4H (4000ppm)   Interagency Collaborative Group on Environmental Carcinogenesis, National Cancer Institute, Memorandum, June 17, 1974Vol. 17JUN1974,
rat LD50 oral 111mg/kg (111mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: DYSPNEA

GASTROINTESTINAL: OTHER CHANGES
National Technical Information Service. Vol. OTS0542011,
rat LDLo intraperitoneal 50mg/kg (50mg/kg)   Farmakologiya i Toksikologiya Vol. 31, Pg. 238, 1968.


Consensus Reports:

 Isopropylamine (CAS NO.75-31-0) can be obtained by aminating isopropyl alcohol with ammonia in presence of a nickel/copper or similar catalyst:

(CH3)2CHOH + NH3 → (CH3)2CHNH2 + H2O


SAFETY PROFILE:

Hazard Codes: HighlyF+,IrritantXi
Risk Statements: 12-36/37/38 
R12:Extremely flammable. 
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 16-26-29 
S16:Keep away from sources of ignition. 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S29:Do not empty into drains.
RIDADR: UN 1221 3/PG 1
WGK Germany: 1
RTECS: NT8400000
F: 34
HazardClass: 3
PackingGroup: I


Standards and Recommendations:

 


Analytical Methods:

 


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