CAS No.:55-31-2

TOXICITY DATA with REFERENCE：

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
guinea pig	LDLo	intravenous	200ug/kg (0.2mg/kg)		Arzneimittel-Forschung. Drug Research. Vol. 13, Pg. 51, 1963.
guinea pig	LDLo	subcutaneous	2mg/kg (2mg/kg)		Arzneimittel-Forschung. Drug Research. Vol. 13, Pg. 51, 1963.
mouse	LD50	intraperitoneal	4664ug/kg (4.664mg/kg)	VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION	Journal of Pharmacology and Experimental Therapeutics. Vol. 90, Pg. 110, 1947.
mouse	LD50	intravenous	140ug/kg (0.14mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES LUNGS, THORAX, OR RESPIRATION: DYSPNEA	European Journal of Pharmacology. Vol. 9, Pg. 289, 1970.
mouse	LD50	subcutaneous	1980ug/kg (1.98mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: EXCITEMENT	Journal of Pharmacology and Experimental Therapeutics. Vol. 87, Pg. 214, 1946.
mouse	LDLo	oral	50mg/kg (50mg/kg)		Arzneimittel-Forschung. Drug Research. Vol. 13, Pg. 51, 1963.
rat	LD50	intraduodenal	35mg/kg (35mg/kg)		Archives Internationales de Pharmacodynamie et de Therapie. Vol. 180, Pg. 155, 1969.
rat	LD50	oral	24mg/kg (24mg/kg)		Archives Internationales de Pharmacodynamie et de Therapie. Vol. 180, Pg. 155, 1969.
rat	LD50	subcutaneous	5mg/kg (5mg/kg)		Archives Internationales de Pharmacodynamie et de Therapie. Vol. 180, Pg. 155, 1969.
rat	LDLo	intravenous	50ug/kg (0.05mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS	Journal of Pharmacology and Experimental Therapeutics. Vol. 24, Pg. 101, 1925.

Consensus Reports：

Reported in NTP Carcinogenesis Studies (Inhalation); Inadequate Study: rat, mouse NTPTR*    National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No. NTP-TR-380 ,1990. .

SAFETY PROFILE：

Poison by ingestion, intravenous, subcutaneous, and intraperitoneal routes. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits very toxic fumes of Cl⁻ and NO_x. See also VASOTONIN and other adrenalin compounds.
Safety Information aboout L-Epinephrine hydrochloride (CAS NO.55-31-2):
RIDADR: 3249
HazardClass: 6.1(a)
PackingGroup: II

Standards and Recommendations：

 

Analytical Methods：