CAS No.:39341-83-8
Name: Luteinizing hormone (human)
Details Introduction
TOXICITY DATA with REFERENCE:
Consensus Reports:
SAFETY PROFILE:
Safety information of Luteinizing hormone (human) (CAS NO.39341-83-8):
Hazard Codes:
T,
B
Risk Statements:
R60: May impair fertility
Safety Statements:
S53: Avoid exposure - obtain special instruction before use
S22: Do not breathe dust
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection
S45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
WGK Germany: 3
RTECS: OK6367000
Standards and Recommendations:
Luteinizing hormone (human) levels are normally low during childhood and, in women, high after menopause. As Luteinizing hormone (human) is secreted as pulses, it is necessary to follow its concentration over a sufficient period of time to get a proper information about its blood level.
During the reproductive years typical levels are between 1-20 IU/L. Physiologic high LH levels are seen during the Luteinizing hormone (human) surge (v.s.); typically they last 48 hours.
Analytical Methods:
Luteinizing hormone (human) can be detected by urinary ovulation predictor kits (OPK, also LH-kit) that are performed, typically daily, around the time ovulation may be expected. The conversion from a negative to a positive reading would suggest that ovulation is about to occur within 24–48 hours, giving women two days to engage in sexual intercourse or artificial insemination with the intentions of conceiving.
Tests may be read manually using a colour-change paper strip, or digitally with the assistance of reading electronics.
Tests for Luteinising hormone may be combined with testing for estradiol in tests such as the Clearblue fertility monitor.
The sensitivity of LH tests are measured in milli international unit, with tests commonly available in the range 10-40 m.i.u.
As sperm can stay viable in the woman for several days, LH tests are not recommended for contraceptive practices, as the LH surge typically occurs after the beginning of the fertile window.
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