CAS No.:519-02-8
Name: Matrine
Details Introduction
TOXICITY DATA with REFERENCE:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intramuscular | 74150ug/kg (74.15mg/kg) | Zhongguo Yaoxue Zazhi. Chinese Pharmacuetical Journal. Vol. 27, Pg. 201, 1992. | |
mouse | LD50 | intraperitoneal | 150mg/kg (150mg/kg) | Zhongcaoyao. Chinese Traditional and Herbal Medicine. Vol. 18, Pg. 214, 1987. | |
mouse | LD50 | intravenous | 64850ug/kg (64.85mg/kg) | Zhongguo Yaoxue Zazhi. Chinese Pharmacuetical Journal. Vol. 27, Pg. 201, 1992. | |
rat | LD50 | intraperitoneal | 125mg/kg (125mg/kg) | Chemical and Pharmaceutical Bulletin. Vol. 18, Pg. 2555, 1970. |
Consensus Reports:
SAFETY PROFILE:
Hazard Codes: Xn
Risk Statements: 20/21/22-37/38-41-48
20/21/22: Harmful by inhalation, in contact with skin and if swallowed
37/38: Irritating to respiratory system and skin
41: Risk of serious damage to eyes
48: Danger of serious damage to health by prolonged exposure
Safety Statements: 22-26-36/37/39-45
22: Do not breathe dust
26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36/37/39: Wear suitable protective clothing, gloves and eye/face protection
45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
Standards and Recommendations:
Analytical Methods:
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