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CAS No.:519-02-8

Name: Matrine

Details Introduction

TOXICITY DATA with REFERENCE:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intramuscular 74150ug/kg (74.15mg/kg)   Zhongguo Yaoxue Zazhi. Chinese Pharmacuetical Journal. Vol. 27, Pg. 201, 1992.
mouse LD50 intraperitoneal 150mg/kg (150mg/kg)   Zhongcaoyao. Chinese Traditional and Herbal Medicine. Vol. 18, Pg. 214, 1987.
mouse LD50 intravenous 64850ug/kg (64.85mg/kg)   Zhongguo Yaoxue Zazhi. Chinese Pharmacuetical Journal. Vol. 27, Pg. 201, 1992.
rat LD50 intraperitoneal 125mg/kg (125mg/kg)   Chemical and Pharmaceutical Bulletin. Vol. 18, Pg. 2555, 1970.
 


Consensus Reports:

 


SAFETY PROFILE:

Hazard Codes: Xn 
Risk Statements: 20/21/22-37/38-41-48
20/21/22: Harmful by inhalation, in contact with skin and if swallowed 
37/38: Irritating to respiratory system and skin
41: Risk of serious damage to eyes 
48: Danger of serious damage to health by prolonged exposure    
Safety Statements: 22-26-36/37/39-45
22: Do not breathe dust
26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36/37/39: Wear suitable protective clothing, gloves and eye/face protection  
45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)


Standards and Recommendations:

 


Analytical Methods:

 


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