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CAS No.:1665-48-1

Name: Metaxalone

Details Introduction

TOXICITY DATA with REFERENCE:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 490mg/kg (490mg/kg)   "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 261, 1972.
mouse LD50 oral 1690mg/kg (1690mg/kg) BEHAVIORAL: MUSCLE WEAKNESS

BEHAVIORAL: REGIDITY

SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 233, Pg. 326, 1978.
rat LD50 intraperitoneal 515mg/kg (515mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 17, Pg. 242, 1967.
rat LD50 oral 775mg/kg (775mg/kg)   "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 261, 1972.


Consensus Reports:

 


SAFETY PROFILE:

 


Standards and Recommendations:

 


Analytical Methods:

 


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