CAS No.:79-22-1
Name: Methyl chloroformate
Details Introduction
TOXICITY DATA with REFERENCE:
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| cat | LCLo | inhalation | 1500mg/m3/30M (1500mg/m3) | Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 42(5), Pg. 97, 1977. | |
| guinea pig | LD50 | oral | 140mg/kg (140mg/kg) | Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 42(5), Pg. 97, 1977. | |
| man | TCLo | inhalation | 5mg/m3 (5mg/m3) | SENSE ORGANS AND SPECIAL SENSES: CONJUNCTIVE IRRITATION: EYE LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES |
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 42(5), Pg. 97, 1977. |
| mouse | LC50 | inhalation | 185mg/m3/2H (185mg/m3) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: EXCITEMENT BEHAVIORAL: MUSCLE WEAKNESS |
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 42(5), Pg. 97, 1977. |
| mouse | LD50 | intraperitoneal | 40mg/kg (40mg/kg) | National Technical Information Service. Vol. AD691-490, | |
| mouse | LD50 | oral | 67mg/kg (67mg/kg) | Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 42(5), Pg. 97, 1977. | |
| mouse | LD50 | skin | 1750mg/kg (1750mg/kg) | Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 42(5), Pg. 97, 1977. | |
| rabbit | LD50 | skin | 7120mg/kg (7120mg/kg) | Toxicology and Applied Pharmacology. Vol. 42, Pg. 417, 1977. | |
| rat | LC50 | inhalation | 88ppm/1H (88ppm) | Toxicology and Applied Pharmacology. Vol. 42, Pg. 417, 1977. | |
| rat | LD50 | oral | 60mg/kg (60mg/kg) | Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 42(5), Pg. 97, 1977. |
Consensus Reports:
SAFETY PROFILE:
Hazard Codes:
F,
T+
Risk Statements: 11-21/22-26-34
R11:Highly flammable.
R21/22:Harmful in contact with skin and if swallowed.
R26:Very toxic by inhalation.
R34:Causes burns.
Safety Statements: 14-26-28-36/37/39-45-63-46-28A-39-36/37
S14:Keep away from ... (a list of incompatible materials will follow).
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S46:If swallowed, seek medical advice immediately and show this container or label.
S28:After contact with skin, wash immediately with plenty of soap-suds.
S39:Wear eye / face protection.
S36/37:Wear suitable protective clothing and gloves.
RIDADR: UN 1238 6.1/PG 1
WGK Germany: 2
F: 10-19-21
HazardClass: 6.1(a)
PackngGroup: I
Standards and Recommendations:
Analytical Methods:
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