CAS No.:127045-41-4

TOXICITY DATA with REFERENCE：

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD	oral	> 2gm/kg (2000mg/kg)		Japanese Journal of Antibiotics. Vol. 48, Pg. 754, 1995.
dog	LDLo	intravenous	400mg/kg (400mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD GASTROINTESTINAL: NAUSEA OR VOMITING	Japanese Journal of Antibiotics. Vol. 48, Pg. 754, 1995.
mouse	LD	oral	> 5gm/kg (5000mg/kg)		Japanese Journal of Antibiotics. Vol. 48, Pg. 754, 1995.
mouse	LD	subcutaneous	> 5gm/kg (5000mg/kg)	SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"	Japanese Journal of Antibiotics. Vol. 48, Pg. 754, 1995.
mouse	LD50	intravenous	783mg/kg (783mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE" LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Japanese Journal of Antibiotics. Vol. 48, Pg. 754, 1995.
rat	LD	oral	> 5gm/kg (5000mg/kg)		Chemotherapy Vol. 43(Suppl,
rat	LD	subcutaneous	> 5gm/kg (5000mg/kg)	SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"	Japanese Journal of Antibiotics. Vol. 48, Pg. 754, 1995.
rat	LD50	intravenous	341mg/kg (341mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Japanese Journal of Antibiotics. Vol. 48, Pg. 754, 1995.

Consensus Reports：

 

SAFETY PROFILE：

Hazard Codes: Xn,C,F
Risk Statements: 20/21/22-34-11
R11: Pazufloxacin (CAS NO.127045-41-4)  is highly flammable. 
R34: Causes burns. 
R20/21/22: Harmful by inhalation, in contact with skin and if swallowed.
Safety Statements: 45-36/37/39-26-16
S16: Keep Pazufloxacin (CAS NO.127045-41-4) away from sources of ignition. 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) 
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection.
RTECS: UU8815300

Standards and Recommendations：

 

Analytical Methods：